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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：187/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
作者:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Deng, Zhenzhen;  Wang, Qingchi;  Zhang, Quanbin
Adobe PDF(3732Kb)  |  收藏  |  浏览/下载：185/0  |  提交时间：2021/12/02
Fucoidans  COVID-19  Pulmonary fibrosis  Epithelial-mesenchymal transition  TGF-beta  PI3K/AKT pathway  
Dietary fibers extracted from Saccharina japonica can improve metabolic syndrome and ameliorate gut microbiota dysbiosis induced by high fat diet 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2021, 卷号: 85, 页码: 11
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(5410Kb)  |  收藏  |  浏览/下载：191/0  |  提交时间：2021/11/30
Dietary fiber  Insulin resistance  Metabolic syndrome  Gut microbiota  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：298/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 13
作者:  Li, Zhi;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(1107Kb)  |  收藏  |  浏览/下载：239/0  |  提交时间：2021/04/12
glycocalyx  vascular complications  diabetes  endothelial dysfunction  enzyme  
Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 3, 页码: 10
作者:  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wu, Ning;  Zhang, Quanbin
Adobe PDF(401Kb)  |  收藏  |  浏览/下载：199/0  |  提交时间：2020/09/23
fucoidan  low-molecular-weight fucoidan  adriamycin  nephrotic syndrome  
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载：264/0  |  提交时间：2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2014, 卷号: 25, 期号: 11, 页码: 1154-1160
作者:  Liu, Jia;  Zheng, Lanhong;  Ma, Leina;  Wang, Bin;  Zhao, Youguang;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载：238/0  |  提交时间：2015/06/11
Oleanolic Acid  Autophagy  Akt  Cancer Prevention  Natural Compounds  
Aplysin Sensitizes Cancer Cells to TRAIL by Suppressing P38 MAPK/Survivin Pathway 期刊论文
MARINE DRUGS, 2014, 卷号: 12, 期号: 9, 页码: 5072-5088
作者:  Liu, Jia;  Ma, Leina;  Wu, Ning;  Liu, Ge;  Zheng, Lanhong;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China.
Adobe PDF(920Kb)  |  收藏  |  浏览/下载：221/0  |  提交时间：2015/06/11
Aplysin  Trail  P38 Mapk  Survivin  
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways 期刊论文
ONCOLOGY REPORTS, 2014, 卷号: 32, 期号: 2, 页码: 567-572
作者:  Liu, Jia;  Zheng, Lanhong;  Zhong, Jiateng;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载：211/0  |  提交时间：2015/06/11
Oleanolic Acid  Autophagy  Cancer  Mammalian Target Of Rapamycin  C-jun N-terminal Kinase