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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
Authors:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
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Fucoidan  Metabolic syndrome  Gut microbiota  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
Authors:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Deng, Zhenzhen;  Wang, Qingchi;  Zhang, Quanbin
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Fucoidans  COVID-19  Pulmonary fibrosis  Epithelial-mesenchymal transition  TGF-beta  PI3K/AKT pathway  
Preparation and Antioxidant Activity of Chitosan Dimers with Different Sequences 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 7, 页码: 15
Authors:  Hao, Wentong;  Li, Kecheng;  Ma, Yuzhen;  Li, Rongfeng;  Xing, Ronge;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2007Kb)  |  Favorite  |  View/Download:55/0  |  Submit date:2021/08/17
chitosan dimers  sequence  separation  biological method  antioxidant activity  
海胆及深海细菌免疫调节活性多糖的发现、结构表征和机制研究 学位论文
理学博士, 生物楼5楼会议室: 中国科学院海洋研究所, 2021
Authors:  王清池
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多糖  海胆  细菌  结构表征  生物活性  
经济海藻裙带菜品种培育和养殖相关问题的研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2021
Authors:  李晓东
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裙带菜,遗传育种, 遗传结构, 碳代谢,虫害  
In vitro and in vivo anti-inflammatory activities of a fucose-rich fucoidan isolated from Saccharina japonica 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 156, 页码: 717-729
Authors:  Ni, Liying;  Wang, Lei;  Fu, Xiaoting;  Duan, Delin;  Jeon, You-Jin;  Xu, Jiachao;  Gao, Xin
Adobe PDF(2376Kb)  |  Favorite  |  View/Download:31/0  |  Submit date:2020/09/25
Saccharine japonica  Fucoidan  Structure  Anti-inflammation  RAW 264.7  Zebrafish  
Genome-wide analysis of the Saccharina japonica sulfotransferase genes and their transcriptional profiles during whole developmental periods and under abiotic stresses 期刊论文
BMC PLANT BIOLOGY, 2020, 卷号: 20, 期号: 1, 页码: 20
Authors:  Lu, Chang;  Shao, Zhanru;  Zhang, Pengyan;  Duan, Delin
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Saccharina japonica  Sulfotransferase  Fucoidan  Transcriptome  Genome  
Protective Effect of a Fucose-Rich Fucoidan Isolated fromSaccharina japonicaagainst Ultraviolet B-Induced Photodamage In Vitro in Human Keratinocytes and In Vivo in Zebrafish 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 6, 页码: 12
Authors:  Su, Wanchun;  Wang, Lei;  Fu, Xiaoting;  Ni, Liying;  Duan, Delin;  Xu, Jiachao;  Gao, Xin
Adobe PDF(2181Kb)  |  Favorite  |  View/Download:24/0  |  Submit date:2020/09/25
ROS  Phaeophyta  carbohydrate  UVB irradiation  HaCaT cells  zebrafish  
海带低分子量褐藻多糖硫酸酯对糖尿病肾病的作用机制研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:  王菁
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低分子量褐藻多糖硫酸酯  糖尿病肾病  纤维连接蛋白  细胞外基质-受体相互作用  肠道菌群  
Degradation of different molecular weight fucoidans and their inhibition of TGF-beta 1 induced epithelial-mesenchymal transition in mouse renal tubular epithelial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 151, 页码: 545-553
Authors:  Li, Xiaosong;  Wu, Ning;  Chen, Yongqiang;  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Qin, Yimin;  Zhang, Quanbin
Adobe PDF(2869Kb)  |  Favorite  |  View/Download:31/0  |  Submit date:2020/09/23
Degradation  Fucoidan  Epithelial-mesenchymal transition  Kidney fibrosis