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Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
Authors:  Deng, Zhenzhen;  Wu, Ning;  Suo, Qishan;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
Favorite  |  View/Download：38/0  |  Submit date：2023/01/04
Capecitabine  Tumor microenvironment  Macrophages  TLR4  Fucoidan  
Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 215, 页码: 253-261
Authors:  Cui, Meiyu;  Li, Xiaohong;  Geng, Lihua;  Wu, Ning;  Wang, Jing;  Deng, Zhenzhen;  Li, Zhi;  Zhang, Quanbin
Favorite  |  View/Download：69/0  |  Submit date：2022/08/17
Fucoidan  Saccharina japonica  Scavenger receptor  Macrophage  SR-A  CD36  LOX-1  Immunomodulatory  
Co-activating the AMPK signaling axis by low molecular weight fucoidan LF2 and fucoxanthin improves the HFD-induced metabolic syndrome in mice 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2022, 卷号: 94, 页码: 9
Authors:  Deng, Zhenzhen;  Wang, Jing;  Wu, Ning;  Geng, Lihua;  Zhang, Quanbin;  Yue, Yang
Favorite  |  View/Download：73/0  |  Submit date：2022/08/17
Fucoxanthin  Fucoidan  Metabolic Syndrome  AMPK Signaling Axis  
Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
Authors:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  Favorite  |  View/Download：72/0  |  Submit date：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
Authors:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Deng, Zhenzhen;  Wang, Qingchi;  Zhang, Quanbin
Adobe PDF(3732Kb)  |  Favorite  |  View/Download：100/0  |  Submit date：2021/12/02
Fucoidans  COVID-19  Pulmonary fibrosis  Epithelial-mesenchymal transition  TGF-beta  PI3K/AKT pathway  
Dietary fibers extracted from Saccharina japonica can improve metabolic syndrome and ameliorate gut microbiota dysbiosis induced by high fat diet 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2021, 卷号: 85, 页码: 11
Authors:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(5410Kb)  |  Favorite  |  View/Download：91/0  |  Submit date：2021/11/30
Dietary fiber  Insulin resistance  Metabolic syndrome  Gut microbiota  
Glucuronomannan GM2 from Saccharina japonica Enhanced Mitochondrial Function and Autophagy in a Parkinson's Model 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 2, 页码: 15
Authors:  Liu, Yingjuan;  Jin, Weihua;  Deng, Zhenzhen;  Zhang, Quanbin;  Wang, Jing
Adobe PDF(3165Kb)  |  Favorite  |  View/Download：117/0  |  Submit date：2021/04/14
glucuronomannan oligosaccharide  Parkinson’  s disease  apoptosis  autophagy  mitochondria  
In vitro evaluation of the neuroprotective effect of oligo-porphyran from Porphyra yezoensis in PC12 cells 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 4, 页码: 2559-2571
Authors:  Liu, YingJuan;  Deng, Zhenzhen;  Geng, Lihua;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(2204Kb)  |  Favorite  |  View/Download：193/0  |  Submit date：2019/11/14
Rhodophyta  Oligo-porphyran  Apoptosis  6-OHDA  PC12 cells  Mitochondria  
两种红藻多肽的抗氧化及降血压活性研究 学位论文
工程硕士, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:  邓真真
Adobe PDF(3421Kb)  |  Favorite  |  View/Download：247/1  |  Submit date：2019/06/18
坛紫菜，龙须菜，抗氧化活性，降血压活性，shr  
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs) 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
Authors:  Deng, Zhenzhen;  Liu, Yingjuan;  Wang, Jing;  Wu, Suhuang;  Geng, Lihua;  Sui, Zhenghong;  Zhang, Quanbin
Adobe PDF(2987Kb)  |  Favorite  |  View/Download：197/0  |  Submit date：2019/08/27
Gracilariopsis lemaneiformis  ACE-inhibitory activity  peptide  molecular docking  SHRs