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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
Authors:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
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Fucoidan  Metabolic syndrome  Gut microbiota  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
Authors:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Deng, Zhenzhen;  Wang, Qingchi;  Zhang, Quanbin
Adobe PDF(3732Kb)  |  Favorite  |  View/Download:33/0  |  Submit date:2021/12/02
Fucoidans  COVID-19  Pulmonary fibrosis  Epithelial-mesenchymal transition  TGF-beta  PI3K/AKT pathway  
Dietary fibers extracted from Saccharina japonica can improve metabolic syndrome and ameliorate gut microbiota dysbiosis induced by high fat diet 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2021, 卷号: 85, 页码: 11
Authors:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
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Dietary fiber  Insulin resistance  Metabolic syndrome  Gut microbiota  
Glucuronomannan GM2 from Saccharina japonica Enhanced Mitochondrial Function and Autophagy in a Parkinson's Model 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 2, 页码: 15
Authors:  Liu, Yingjuan;  Jin, Weihua;  Deng, Zhenzhen;  Zhang, Quanbin;  Wang, Jing
Adobe PDF(3165Kb)  |  Favorite  |  View/Download:50/0  |  Submit date:2021/04/14
glucuronomannan oligosaccharide  Parkinson’  s disease  apoptosis  autophagy  mitochondria  
In vitro evaluation of the neuroprotective effect of oligo-porphyran from Porphyra yezoensis in PC12 cells 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 4, 页码: 2559-2571
Authors:  Liu, YingJuan;  Deng, Zhenzhen;  Geng, Lihua;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(2204Kb)  |  Favorite  |  View/Download:118/0  |  Submit date:2019/11/14
Rhodophyta  Oligo-porphyran  Apoptosis  6-OHDA  PC12 cells  Mitochondria  
两种红藻多肽的抗氧化及降血压活性研究 学位论文
工程硕士, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:  邓真真
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坛紫菜,龙须菜,抗氧化活性,降血压活性,shr  
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs) 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
Authors:  Deng, Zhenzhen;  Liu, Yingjuan;  Wang, Jing;  Wu, Suhuang;  Geng, Lihua;  Sui, Zhenghong;  Zhang, Quanbin
Adobe PDF(2987Kb)  |  Favorite  |  View/Download:108/0  |  Submit date:2019/08/27
Gracilariopsis lemaneiformis  ACE-inhibitory activity  peptide  molecular docking  SHRs