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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
Authors:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
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Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture 期刊论文
VIRULENCE, 2021, 卷号: 12, 期号: 1, 页码: 1362-1376
Authors:  Zhao, Yan;  Jiang, Shuai;  Zhang, Jian;  Guan, Xiao-Lu;  Sun, Bo-Guang;  Sun, Li
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Bacillus cereus  deep-sea cold seep  infection  NLRP3 inflammasome  pyroptosis  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
Authors:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
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PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Seasonal and Spatial Variation of Pelagic Microbial Food Web Structure in a Semi-Enclosed Temperate Bay 期刊论文
FRONTIERS IN MARINE SCIENCE, 2020, 卷号: 7, 页码: 14
Authors:  Li, Haibo;  Chen, Xue;  Denis, Michel;  Zhao, Yuan;  Huang, Lingfeng;  Jiang, Zengjie;  Zhang, Wuchang;  Xiao, Tian
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microbial food web  structure  seasonal  spatial  variation  Sanggou Bay  
Petrogenesis of Early Cretaceous adakites in Tongguanshan Cu-Au polymetallic deposit, Tongling region, Eastern China 期刊论文
ORE GEOLOGY REVIEWS, 2020, 卷号: 126, 页码: 17
Authors:  Jiang, Xiao-Yan;  Deng, Jiang-Hong;  Luo, Jin-Cheng;  Zhang, Li-Peng;  Luo, Ze-Bin;  Yan, Hai-Bo;  Sun, Wei-Dong
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Adakite  Geochemistry  Cu-Au mineralization  Tongguanshan deposit  Tongling  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
Authors:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
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bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
Authors:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
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CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Comparative analysis of mitochondrial genome of a deep-sea crab Chaceon granulates reveals positive selection and novel genetic features 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 2, 页码: 427-437
Authors:  Zhang, Bo;  Wu, Yingying;  Wang, Xin;  Jiang, Wei;  Yin, Jianping;  Lin, Qiang
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deep-sea organisms  mitochondrial genome  adaptation  Chaceon granulates  
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats 期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 6, 页码: 3429-3437
Authors:  Guo, Shuju;  Wang, Lijun;  Chen, Dong;  Jiang, Bo
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Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
Authors:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
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