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Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats 期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 6, 页码: 3429-3437
Authors:  Guo, Shuju;  Wang, Lijun;  Chen, Dong;  Jiang, Bo
Favorite  |  View/Download:11/0  |  Submit date:2020/03/20
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
Authors:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Favorite  |  View/Download:9/0  |  Submit date:2020/03/20
A Comparative Analysis of Edwardsiella tarda-Induced Transcriptome Profiles in RAW264.7 Cells Reveals New Insights into the Strategy of Bacterial Immune Evasion 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 22, 页码: 20
Authors:  Li, Huili;  Sun, Boguang;  Ning, Xianhui;  Jiang, Shuai;  Sun, Li
Favorite  |  View/Download:4/0  |  Submit date:2020/03/20
Edwardsiella tarda  macrophage  infection  transcriptome  immune evasion  
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
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Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
Analysis of Nonlinear Variation of Chlorophyll Fluorescence with Saturated Excitation and Its Influence on Chlorophyll Concentration Chlorophyll Concentration Measurement by LIF 期刊论文
SPECTROSCOPY AND SPECTRAL ANALYSIS, 2019, 卷号: 39, 期号: 8, 页码: 2366-2370
Authors:  Li Xiao-long;  He Yan;  Chen Wei-biao;  Jiang Jing-bo;  Liu Qing-kui;  Chen Yong-hua
Adobe PDF(1468Kb)  |  Favorite  |  View/Download:12/0  |  Submit date:2020/01/03
Laser induced fluorescence (LIF)  Chlorophyll concentration  Saturated excitation  Nonlinear fluorescence  Raman scattering  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
Authors:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Favorite  |  View/Download:10/0  |  Submit date:2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
Authors:  Guo, Chuanlong;  Wang, Lijun;  Li, Xinxue;  Wang, Shuaiyu;  Yu, Xuemin;  Xu, Kuo;  Zhao, Yue;  Luo, Jiao;  Li, Xiangqian;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:17/0  |  Submit date:2019/08/28
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
Authors:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:22/0  |  Submit date:2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Mid-late Holocene rainfall variation in Taiwan: A high-resolution multi proxy record unravels the dual influence of the Asian monsoon and ENSO 期刊论文
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY, 2019, 卷号: 516, 页码: 139-151
Authors:  Chen, Jinxia;  Li, Tiegang;  Nan, Qingyun;  Shi, Xuefa;  Liu, Yanguang;  Jiang, Bo;  Zou, Jianjun;  Selvaraj, Kandasamy;  Li, Dongling;  Li, Chuanshun
Favorite  |  View/Download:19/0  |  Submit date:2019/08/27
Fern spore  C/N ratio  La Nina  Tropical cyclone  Okinawa Trough  
CYC27 Synthetic Derivative of Bromophenol from Red Alga Rhodomela confervoides: Anti-Diabetic Effects of Sensitizing Insulin Signaling Pathways and Modulating RNA Splicing-Associated RBPs 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 15
Authors:  Luo, Jiao;  Jiang, Bo;  Li, Chao;  Jia, Xiaoling;  Shi, Dayong
Favorite  |  View/Download:13/0  |  Submit date:2019/08/28
brominated organic compounds  hypoglycemic activity  insulin-sensitizing effect  RBPs  RNA splicing