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Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
Authors:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
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Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells 期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
Authors:  Guo, Chuanlong;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
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antiangiogenesis  curcumin analogs  hypoxia-inducible factor-1 alpha  human umbilical vein endothelial cells  vascular endothelial growth factor  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
Authors:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
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Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
Authors:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
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Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
Authors:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
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Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
Authors:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
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Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
Scallop genome provides insights into evolution of bilaterian karyotype and development 期刊论文
NATURE ECOLOGY & EVOLUTION, 2017, 卷号: 1, 期号: 5
Authors:  Wang, Shi;  Zhang, Jinbo;  Jiao, Wenqian;  Li, Ji;  Xun, Xiaogang;  Sun, Yan;  Guo, Ximing;  Huan, Pin;  Dong, Bo;  Zhang, Lingling;  Hu, Xiaoli;  Sun, Xiaoqing;  Wang, Jing;  Zhao, Chengtian;  Wang, Yangfan;  Wang, Dawei;  Huang, Xiaoting;  Wang, Ruijia;  Lv, Jia;  Li, Yuli;  Zhang, Zhifeng;  Liu, Baozhong;  Lu, Wei;  Hui, Yuanyuan;  Liang, Jun;  Zhou, Zunchun;  Hou, Rui;  Li, Xue;  Liu, Yunchao;  Li, Hengde;  Ning, Xianhui;  Lin, Yu;  Zhao, Liang;  Xing, Qiang;  Dou, Jinzhuang;  Li, Yangping;  Mao, Junxia;  Guo, Haobing;  Dou, Huaiqian;  Li, Tianqi;  Mu, Chuang;  Jiang, Wenkai;  Fu, Qiang;  Fu, Xiaoteng;  Miao, Yan;  Liu, Jian;  Yu, Qian;  Li, Ruojiao;  Liao, Huan;  Li, Xuan;  Kong, Yifan;  Jiang, Zhi;  Chourrout, Daniel;  Li, Ruiqiang;  Bao, Zhenmin
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Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 8, 页码: 683-692
Authors:  Wang, Bao-Cheng;  Wang, Li-Jun;  Jiang, Bo;  Wang, Shuai-Yu;  Wu, Ning;  Li, Xiang-Qian;  Shi, Da-Yong
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Application Of Fluorine  Anticancer  Antimicrobial  Anti-inflammatory  Antivirus Activity  Drug Design  Importance Of Fluorinated Compounds  
A review of the components of brown seaweeds as potential candidates in cancer therapy 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 15, 页码: 12592-12610
Authors:  Hussain, Ejaz;  Wang, Li-Jun;  Jiang, Bo;  Riaz, Saba;  Butt, Ghazala Yasmeen;  Shi, Da-Yong
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Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells 期刊论文
TUMOR BIOLOGY, 2015, 卷号: 36, 期号: 12, 页码: 9667-9676
Authors:  Wu, Ning;  Liu, Jia;  Zhao, Xiangzhong;  Yan, Zhiyong;  Jiang, Bo;  Wang, Lijun;  Cao, Shousong;  Shi, Dayong;  Lin, Xiukun
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Cardamonin  Glioblastoma Stem Cell  Stat3  Apoptosis  Temozolomide  Self-renewal