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A novel dibenzo[a,c]phenazine-based fluorescent probe for fast and selective detection of thiophenols in environmental water 期刊论文
RSC ADVANCES, 2022, 卷号: 12, 期号: 14, 页码: 8611-8616
Authors:  Guo, Shuju;  Wang, Lijun;  Jiang, Bo
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DFT and Raman study of all-trans astaxanthin optical isomers 期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2021, 卷号: 262, 页码: 8
Authors:  Yao, Guohua;  Guo, Shuju;  Yu, Wenjie;  Muhammad, Muhammad;  Liu, Jianguo;  Huang, Qing
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All-trans astaxanthin  Optical isomers  Raman spectroscopy  DFT  Chiral  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
Authors:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
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Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
Authors:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
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PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
Authors:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  Favorite  |  View/Download:135/0  |  Submit date:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
Authors:  Zhang, Jiajia;  Dai, Jiajia;  Zheng, Qingxuan;  Guo, Shuju;  Yu, Yanyan;  Hu, Wenpeng;  Gao, Yanan;  Shi, Dayong
Adobe PDF(2858Kb)  |  Favorite  |  View/Download:41/0  |  Submit date:2020/09/23
triple negative breast cancer  MDA-MB-231 cells  fluoro-thiazolylhydrazone  MAPK pathway  phosphorylated p44/42 MAPK (ERK1/2)  phosphorylated c-Jun N-terminal kinase (p-JNK)  apoptosis  
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats 期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 6, 页码: 3429-3437
Authors:  Guo, Shuju;  Wang, Lijun;  Chen, Dong;  Jiang, Bo
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Chalcone-analogue fluorescent probes for detecting thiophenols in seawater samples 期刊论文
TALANTA, 2019, 卷号: 201, 页码: 301-308
Authors:  Liu, Hua;  Guo, Chuanlong;  Guo, Shuju;  Fan, Junting;  Wang, Lijun;  Shi, Dayong
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Fluorescent probe  Thiophenol  Seawater sample  Chalcone  
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
Authors:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
Favorite  |  View/Download:117/0  |  Submit date:2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Discovery of Natural Dimeric Naphthopyrones as Potential Cytotoxic Agents through ROS-Mediated Apoptotic Pathway 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 11
Authors:  Xu, Kuo;  Guo, Chuanlong;  Meng, Jie;  Tian, Haiying;  Guo, Shuju;  Shi, Dayong
Adobe PDF(3680Kb)  |  Favorite  |  View/Download:119/0  |  Submit date:2019/08/28
Aspergillus  naphthopyrones  cytotoxicity  endophytic fungus  Leathesia nana