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Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
Authors:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
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Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells 期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
Authors:  Guo, Chuanlong;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
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antiangiogenesis  curcumin analogs  hypoxia-inducible factor-1 alpha  human umbilical vein endothelial cells  vascular endothelial growth factor  
The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade 期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 1, 页码: 55-69
Authors:  Xu, Qi;  Wang, Lijun;  Luo, Jiao;  Shi, Dayong
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Type 2 Diabetes Mellitus  Insulin Resistance  Insulin Secretion  Targets  Mechanism  Drugs  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
Authors:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
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Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
Authors:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
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Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
Authors:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
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Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
The design strategy of selective PTP1B inhibitors over TCPTP 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 16, 页码: 3343-3352
Authors:  Li, XiangQian;  Wang, LiJun;  Shi, DaYong
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Selectivity  Ptp1b Inhibitor  Tcptp  Diabetes  Design Strategy  
Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells 期刊论文
TUMOR BIOLOGY, 2015, 卷号: 36, 期号: 12, 页码: 9667-9676
Authors:  Wu, Ning;  Liu, Jia;  Zhao, Xiangzhong;  Yan, Zhiyong;  Jiang, Bo;  Wang, Lijun;  Cao, Shousong;  Shi, Dayong;  Lin, Xiukun
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Cardamonin  Glioblastoma Stem Cell  Stat3  Apoptosis  Temozolomide  Self-renewal  
The late Cenozoic deep-water channel system in the Baiyun Sag, Pearl River Mouth Basin: Development and tectonic effects 期刊论文
DEEP-SEA RESEARCH PART II-TOPICAL STUDIES IN OCEANOGRAPHY, 2015, 卷号: 122, 期号: 2015, 页码: 226-239
Authors:  Ma, Benjun;  Wu, Shiguo;  Sun, Qiliang;  Mi, Lijun;  Wang, ZhenZhen;  Tian, Jie
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Deep-water Channel  Active Fault  Turbidity Deposits  Deep-water Sedimentation  Pearl River Mouth Basin  
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 7, 页码: 4452-4469
Authors:  Luo, Jiao;  Wu, Ning;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Wang, Baocheng;  Wang, Changhui;  Shi, Dayong
Adobe PDF(1638Kb)  |  Favorite  |  View/Download:81/2  |  Submit date:2015/12/07