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RNA-seq between asexual archeospores and meiosis-related conchospores in Neopyropia yezoensis using Smart-seq2 期刊论文
JOURNAL OF PHYCOLOGY, 2021, 页码: 11
Authors:  He, Bangxiang;  Gu, Wenhui;  Wang, Lijun;  Zheng, Zhenbing;  Shao, Zhizhuo;  Huan, Li;  Zhang, Baoyu;  Ma, Yingchao;  Niu, Jianfeng;  Xie, Xiujun;  Wang, Guangce
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archeospores  asexual reproduction  conchospores  meiosis  RNA-seq  Smart-seq2  
Photosynthesis acclimation under severely fluctuating light conditions allows faster growth of diatoms compared with dinoflagellates 期刊论文
BMC PLANT BIOLOGY, 2021, 卷号: 21, 期号: 1, 页码: 14
Authors:  Zhou, Lu;  Wu, Songcui;  Gu, Wenhui;  Wang, Lijun;  Wang, Jing;  Gao, Shan;  Wang, Guangce
Adobe PDF(4826Kb)  |  Favorite  |  View/Download：7/0  |  Submit date：2021/05/26
Diatoms  Dinoflagellates  Fluctuating light  Pioneer bloom  PGR5  Phaeodactylum tricornutum  Phytoplankton bloom succession  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
Authors:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  Favorite  |  View/Download：7/0  |  Submit date：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
Authors:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun;  Fan, Junting;  Di, Guohu;  Guo, Chuanlong
Adobe PDF(8144Kb)  |  Favorite  |  View/Download：6/0  |  Submit date：2021/04/21
PARP inhibitor  BRCA  Pancreatic cancer  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
Authors:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  Favorite  |  View/Download：35/0  |  Submit date：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
Authors:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  Favorite  |  View/Download：25/0  |  Submit date：2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
The development of a new real-time subsurface mooring 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 12
Authors:  Wang, Fan;  Wang, Jianing;  Xu, Lijun;  Zhang, Xiangguang;  Yan, Shefeng;  Chen, Yonghua
Adobe PDF(8237Kb)  |  Favorite  |  View/Download：22/0  |  Submit date：2020/09/25
real-time subsurface mooring  underwater acoustic communication  Western Pacific  ocean and climate predictions  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
Authors:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  Favorite  |  View/Download：9/0  |  Submit date：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
Authors:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  Favorite  |  View/Download：8/0  |  Submit date：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
Authors:  Guo, Chuanlong;  Hou, Yuzhen;  Yu, Xuemin;  Zhang, Fan;  Wu, Xiaochen;  Wu, Xianggen;  Wang, Lijun
Favorite  |  View/Download：10/0  |  Submit date：2020/09/22
Apoptosis  eIF4F  ERK  MNK  A549 cells