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Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Favorite  |  View/Download:21/0  |  Submit date:2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 17
Authors:  Su, Jingqian;  Guo, Kai;  Huang, Min;  Liu, Yixuan;  Zhang, Jie;  Sun, Lijun;  Li, Daliang;  Pang, Ka-Lai;  Wang, Guangce;  Chen, Long;  Liu, Zhiyu;  Chen, Youqiang;  Chen, Qi;  Huang, Luqiang
Favorite  |  View/Download:2/0  |  Submit date:2020/01/03
fucoxanthin  lipopolysaccharide  nuclear factor-kappa B  sepsis  Conticribra weissflogii  
Chalcone-analogue fluorescent probes for detecting thiophenols in seawater samples 期刊论文
TALANTA, 2019, 卷号: 201, 页码: 301-308
Authors:  Liu, Hua;  Guo, Chuanlong;  Guo, Shuju;  Fan, Junting;  Wang, Lijun;  Shi, Dayong
Favorite  |  View/Download:15/0  |  Submit date:2019/08/29
Fluorescent probe  Thiophenol  Seawater sample  Chalcone  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
Authors:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Favorite  |  View/Download:5/0  |  Submit date:2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
Authors:  Guo, Chuanlong;  Wang, Lijun;  Li, Xinxue;  Wang, Shuaiyu;  Yu, Xuemin;  Xu, Kuo;  Zhao, Yue;  Luo, Jiao;  Li, Xiangqian;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:10/0  |  Submit date:2019/08/28
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
Authors:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:17/0  |  Submit date:2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2, 页码: 14
Authors:  Liu, Hua;  Guo, Chuanlong;  Guo, Shuju;  Wang, Lijun;  Shi, Dayong
Favorite  |  View/Download:5/0  |  Submit date:2019/08/27
fluorescent probe  thiophenol  water samples  chalcone  living cells  
基于pac修饰的氧化石墨烯负载纳米pt构建新型三维过氧化氢电化学传感器 期刊论文
分析测试学报, 2019, 卷号: 38, 期号: 9, 页码: 1029
Authors:  王应霞;  于颖;  李军;  彭全材;  俞立东;  宋金明
Favorite  |  View/Download:0/0  |  Submit date:2020/01/03
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells 期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
Authors:  Guo, Chuanlong;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Favorite  |  View/Download:14/0  |  Submit date:2019/05/15
antiangiogenesis  curcumin analogs  hypoxia-inducible factor-1 alpha  human umbilical vein endothelial cells  vascular endothelial growth factor  
The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade 期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 1, 页码: 55-69
Authors:  Xu, Qi;  Wang, Lijun;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2267Kb)  |  Favorite  |  View/Download:33/0  |  Submit date:2018/04/02
Type 2 Diabetes Mellitus  Insulin Resistance  Insulin Secretion  Targets  Mechanism  Drugs