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Degradation of different molecular weight fucoidans and their inhibition of TGF-beta 1 induced epithelial-mesenchymal transition in mouse renal tubular epithelial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 151, 页码: 545-553
Authors:  Li, Xiaosong;  Wu, Ning;  Chen, Yongqiang;  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Qin, Yimin;  Zhang, Quanbin
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Degradation  Fucoidan  Epithelial-mesenchymal transition  Kidney fibrosis  
Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 3, 页码: 10
Authors:  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wu, Ning;  Zhang, Quanbin
Favorite  |  View/Download:2/0  |  Submit date:2020/09/23
fucoidan  low-molecular-weight fucoidan  adriamycin  nephrotic syndrome  
In vitro evaluation of the neuroprotective effect of oligo-porphyran from Porphyra yezoensis in PC12 cells 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 4, 页码: 2559-2571
Authors:  Liu, YingJuan;  Deng, Zhenzhen;  Geng, Lihua;  Wang, Jing;  Zhang, Quanbin
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Rhodophyta  Oligo-porphyran  Apoptosis  6-OHDA  PC12 cells  Mitochondria  
Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies 期刊论文
GLYCANS AND GLYCOSAMINOGLYCANS AS CLINICAL BIOMARKERS AND THERAPEUTICS, PT B, 2019, 卷号: 163, 页码: 95-111
Authors:  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Zhang, Quanbin
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A heteropolysaccharide from Saccharina japonica with immunomodulatory effect on RAW 264.7 cells 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 557-565
Authors:  Geng, Lihua;  Hu, Weicheng;  Liu, Yingjuan;  Wang, Jing;  Zhang, Quanbin
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Saccharina japonica  Polysaccharide  Immunomodulatory activity  Macrophage  
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs) 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
Authors:  Deng, Zhenzhen;  Liu, Yingjuan;  Wang, Jing;  Wu, Suhuang;  Geng, Lihua;  Sui, Zhenghong;  Zhang, Quanbin
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Gracilariopsis lemaneiformis  ACE-inhibitory activity  peptide  molecular docking  SHRs  
Glucofucogalactan, a heterogeneous low-sulfated polysaccharide from Saccharina japonica and its bioactivity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 90-97
Authors:  Geng, Lihua;  Zhang, Quanbin;  Wang, Jing;  Jin, Weihua;  Zhao, Tingting;  Hu, Weicheng
Adobe PDF(1252Kb)  |  Favorite  |  View/Download:30/0  |  Submit date:2019/08/21
Saccharina japonica  Heteropolysaccharide  Aristolochic acid  Immunomodulation  
海带多糖酸解产物的分离分析及免疫调节作用研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2018
Authors:  耿丽华
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海带  酸性多糖  硫酸化岩藻寡糖  杂多糖  结构分析  质谱  免疫调节  
Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 3, 页码: 16
Authors:  Liu, Yingjuan;  Geng, Lihua;  Zhang, Jingjing;  Wang, Jing;  Zhang, Qi;  Duan, Delin;  Zhang, Quanbin
Adobe PDF(4919Kb)  |  Favorite  |  View/Download:24/0  |  Submit date:2019/08/21
oligo-porphyran  PI3K/Akt  apoptosis  Parkinson's disease  neurobehavior  
Comparative study of the effect of different fucoidans from Sargassum maclurei and Saccharina japonica on FGFs/FGFR signaling activation in BaF3 cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 107, 页码: 2429-2435
Authors:  Geng, Lihua;  Hou, Ningning;  Zhang, Meng;  Xu, Yingjie;  Zhang, Qi;  Wang, Jing;  Zhang, Lijuan;  Zhang, Quanbin
Adobe PDF(1308Kb)  |  Favorite  |  View/Download:23/0  |  Submit date:2019/08/21
Fucoidan  Sulfated polysaccharides  Fibroblast growth factor (FGF)  Fibroblast growth factor receptor (FGFR)