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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：186/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
作者:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Deng, Zhenzhen;  Wang, Qingchi;  Zhang, Quanbin
Adobe PDF(3732Kb)  |  收藏  |  浏览/下载：184/0  |  提交时间：2021/12/02
Fucoidans  COVID-19  Pulmonary fibrosis  Epithelial-mesenchymal transition  TGF-beta  PI3K/AKT pathway  
Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 3, 页码: 10
作者:  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wu, Ning;  Zhang, Quanbin
Adobe PDF(401Kb)  |  收藏  |  浏览/下载：199/0  |  提交时间：2020/09/23
fucoidan  low-molecular-weight fucoidan  adriamycin  nephrotic syndrome  
In vitro evaluation of the neuroprotective effect of oligo-porphyran from Porphyra yezoensis in PC12 cells 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 4, 页码: 2559-2571
作者:  Liu, YingJuan;  Deng, Zhenzhen;  Geng, Lihua;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(2204Kb)  |  收藏  |  浏览/下载：332/0  |  提交时间：2019/11/14
Rhodophyta  Oligo-porphyran  Apoptosis  6-OHDA  PC12 cells  Mitochondria  
Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies 期刊论文
GLYCANS AND GLYCOSAMINOGLYCANS AS CLINICAL BIOMARKERS AND THERAPEUTICS, PT B, 2019, 卷号: 163, 页码: 95-111
作者:  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Zhang, Quanbin
Adobe PDF(399Kb)  |  收藏  |  浏览/下载：236/0  |  提交时间：2020/01/03
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs) 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
作者:  Deng, Zhenzhen;  Liu, Yingjuan;  Wang, Jing;  Wu, Suhuang;  Geng, Lihua;  Sui, Zhenghong;  Zhang, Quanbin
Adobe PDF(2987Kb)  |  收藏  |  浏览/下载：307/0  |  提交时间：2019/08/27
Gracilariopsis lemaneiformis  ACE-inhibitory activity  peptide  molecular docking  SHRs  
Glucofucogalactan, a heterogeneous low-sulfated polysaccharide from Saccharina japonica and its bioactivity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 90-97
作者:  Geng, Lihua;  Zhang, Quanbin;  Wang, Jing;  Jin, Weihua;  Zhao, Tingting;  Hu, Weicheng
Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：291/0  |  提交时间：2019/08/21
Saccharina japonica  Heteropolysaccharide  Aristolochic acid  Immunomodulation  
Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 3, 页码: 16
作者:  Liu, Yingjuan;  Geng, Lihua;  Zhang, Jingjing;  Wang, Jing;  Zhang, Qi;  Duan, Delin;  Zhang, Quanbin
Adobe PDF(4919Kb)  |  收藏  |  浏览/下载：282/0  |  提交时间：2019/08/21
oligo-porphyran  PI3K/Akt  apoptosis  Parkinson's disease  neurobehavior