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Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
Authors:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
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bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
四株深海真菌次级代谢产物化学多样性及生物活性研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:  迟路坪
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深海真菌  海洋天然产物  次级代谢产物  生物活性  
卤代噻唑胺基类化合物的抗三阴性乳腺癌活性研究 学位论文
工学硕士学位, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:  张佳佳
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卤代噻唑  抗肿瘤  三阴性乳腺癌  Mda-mb-231  
牙鲆17β-羟类固醇脱氢酶家族基因特征、表达与功能的初步研究 学位论文
, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:  邹聪聪
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牙鲆(paralichthys Olivaceus)  Hsd17b  基因特征与表达  性腺发育  性腺分化  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
Authors:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
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PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
Authors:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
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CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Slow zeaxanthin accumulation and the enhancement of CP26 collectively contribute to an atypical non-photochemical quenching in macroalga Ulva prolifera under high light 期刊论文
JOURNAL OF PHYCOLOGY, 2020, 页码: 11
Authors:  Gao, Shan;  Zheng, Zhenbing;  Wang, Jing;  Wang, Guangce
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CP24  Green macroalgae  NPQ  Photoprotection  Ulva prolifera  Xanthophyll cycle  
《2019研究前沿》 其他
2019-11-26
Authors:  中国科学院科技战略咨询研究院等
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Cloning and comparative studies of proliferating cell nuclear antigen (PCNA) genes for nine dinoflagellates 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 5, 页码: 2969-2979
Authors:  Deng, Yunyan;  Hu, Zhangxi;  Chai, Zhaoyang;  Tang, Ying Zhong
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Dinoflagellate  Harmful algal blooms (HABs)  Proliferating cell nuclear antigen (PCNA)  Resting cyst  Scrippsiella trochoidea  
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
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Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS