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中国科学院海洋研究所机构知识库
Knowledge Management System Of Institute of Oceanology, Chinese Academy of Sciences
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Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
Authors:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
;
Wang, Lijun
;
Li, Xiangqian
;
Yu, Rilei
;
Shi, Dayong
Adobe PDF(42653Kb)
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Submit date:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
四株深海真菌次级代谢产物化学多样性及生物活性研究
学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:
迟路坪
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Submit date:2020/06/10
深海真菌
海洋天然产物
次级代谢产物
生物活性
卤代噻唑胺基类化合物的抗三阴性乳腺癌活性研究
学位论文
工学硕士学位, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:
张佳佳
Adobe PDF(1995Kb)
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Submit date:2020/06/11
卤代噻唑
抗肿瘤
三阴性乳腺癌
Mda-mb-231
牙鲆17β-羟类固醇脱氢酶家族基因特征、表达与功能的初步研究
学位论文
, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:
邹聪聪
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Submit date:2020/06/09
牙鲆(paralichthys Olivaceus)
Hsd17b
基因特征与表达
性腺发育
性腺分化
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
Authors:
Guo, Chuanlong
;
Zhang, Fan
;
Wu, Xiaochen
;
Yu, Xuemin
;
Wu, Xianggen
;
Shi, Dayong
;
Wang, Lijun
Adobe PDF(1767Kb)
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Submit date:2020/09/23
PARP-1 inhibitor
DNA double-strand breaks
HCC-1937
In vivo
Apoptosis
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes
期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
Authors:
Luo, Jiao
;
Hou, Yufei
;
Xie, Mengyue
;
Ma, Wanli
;
Shi, Dayong
;
Jiang, Bo
Adobe PDF(2455Kb)
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Submit date:2020/09/25
CYC31
PTP1B inhibitor
insulin resistance
fatty acid oxidization
Slow zeaxanthin accumulation and the enhancement of CP26 collectively contribute to an atypical non-photochemical quenching in macroalga Ulva prolifera under high light
期刊论文
JOURNAL OF PHYCOLOGY, 2020, 页码: 11
Authors:
Gao, Shan
;
Zheng, Zhenbing
;
Wang, Jing
;
Wang, Guangce
Adobe PDF(1089Kb)
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View/Download:31/0
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Submit date:2020/03/20
CP24
Green macroalgae
NPQ
Photoprotection
Ulva prolifera
Xanthophyll cycle
《2019研究前沿》
其他
2019-11-26
Authors:
中国科学院科技战略咨询研究院等
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Submit date:2019/11/27
Cloning and comparative studies of proliferating cell nuclear antigen (PCNA) genes for nine dinoflagellates
期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2019, 卷号: 31, 期号: 5, 页码: 2969-2979
Authors:
Deng, Yunyan
;
Hu, Zhangxi
;
Chai, Zhaoyang
;
Tang, Ying Zhong
Adobe PDF(499Kb)
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View/Download:3/0
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Submit date:2020/09/21
Dinoflagellate
Harmful algal blooms (HABs)
Proliferating cell nuclear antigen (PCNA)
Resting cyst
Scrippsiella trochoidea
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
;
Xu, Kuo
;
Jiang, Bo
;
Jia, Xiaoling
;
Li, Chao
;
Shi, Dayong
Adobe PDF(4835Kb)
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View/Download:47/0
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Submit date:2019/08/29
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional agents
eIF4E/eIF4G interaction
Autophagy
ROS