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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：201/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：178/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
In vitro and in vivo anti-inflammatory activities of a fucose-rich fucoidan isolated from Saccharina japonica 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 156, 页码: 717-729
作者:  Ni, Liying;  Wang, Lei;  Fu, Xiaoting;  Duan, Delin;  Jeon, You-Jin;  Xu, Jiachao;  Gao, Xin
Adobe PDF(2376Kb)  |  收藏  |  浏览/下载：175/0  |  提交时间：2020/09/25
Saccharine japonica  Fucoidan  Structure  Anti-inflammation  RAW 264.7  Zebrafish  
Integrated proteomics and metabolomics analysis reveals the antifungal mechanism of the C-coordinated O-carboxymethyl chitosan Cu (II) complex 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 155, 页码: 1491-1509
作者:  Ma, Yuzhen;  Yu, Huahua;  Liu, Weixiang;  Qin, Yukun;  Xing, Ronge;  Li, Pengcheng
Adobe PDF(13837Kb)  |  收藏  |  浏览/下载：241/0  |  提交时间：2020/09/24
Natural organic-based copper  O-CSLn-Cu  Phytophthora capsici Leonian  Proteomics-metabonomics integrated analysis  Antifungal mechanism  
Degradation of different molecular weight fucoidans and their inhibition of TGF-beta 1 induced epithelial-mesenchymal transition in mouse renal tubular epithelial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 151, 页码: 545-553
作者:  Li, Xiaosong;  Wu, Ning;  Chen, Yongqiang;  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Qin, Yimin;  Zhang, Quanbin
Adobe PDF(2869Kb)  |  收藏  |  浏览/下载：204/0  |  提交时间：2020/09/23
Degradation  Fucoidan  Epithelial-mesenchymal transition  Kidney fibrosis  
Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 304-314
作者:  Wang, Jing;  Zhang, Quanbin;  Li, Shuang;  Chen, Zhihang;  Tan, Jiaojiao;  Yao, Jianting;  Duan, Delin
Adobe PDF(2307Kb)  |  收藏  |  浏览/下载：177/0  |  提交时间：2020/09/23
Fucoidan  ECM-receptor interaction  Fibronectin  
Glucofucogalactan, a heterogeneous low-sulfated polysaccharide from Saccharina japonica and its bioactivity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 90-97
作者:  Geng, Lihua;  Zhang, Quanbin;  Wang, Jing;  Jin, Weihua;  Zhao, Tingting;  Hu, Weicheng
Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：304/0  |  提交时间：2019/08/21
Saccharina japonica  Heteropolysaccharide  Aristolochic acid  Immunomodulation  
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载：231/0  |  提交时间：2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes  
Low molecular weight fucoidan and its fractions inhibit renal epithelial mesenchymal transition induced by TGF-beta 1 or FGF-2 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 105, 页码: 1482-1490
作者:  Li, Xinpeng;  Li, Xiaohong;  Zhang, Quanbin;  Zhao, Tingting
Adobe PDF(1196Kb)  |  收藏  |  浏览/下载：303/1  |  提交时间：2018/01/11
Low Molecular Weight Fucoidan  Renal Fibrosis  Epithelial-mesenchymal Transition  
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2016, 卷号: 91, 页码: 233-240
作者:  Xu, Yingjie;  Zhang, Quanbin;  Luo, Dali;  Wang, Jing;  Duan, Delin
Adobe PDF(2577Kb)  |  收藏  |  浏览/下载：211/1  |  提交时间：2016/11/22
Fucoidan  Diabetic Nephropathy  P-selectin