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Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 10
作者:  Shi, Xiaolin;  Li, Xiaowei;  Li, Xiangqian;  Shi, Dayong
Adobe PDF(988Kb)  |  收藏  |  浏览/下载：272/0  |  提交时间：2020/01/03
C-H functionalization  trifluoromethylation  indoles  copper  radical reaction  
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Adobe PDF(4835Kb)  |  收藏  |  浏览/下载：331/0  |  提交时间：2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
收藏  |  浏览/下载：326/0  |  提交时间：2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
作者:  Guo, Chuanlong;  Wang, Lijun;  Li, Xinxue;  Wang, Shuaiyu;  Yu, Xuemin;  Xu, Kuo;  Zhao, Yue;  Luo, Jiao;  Li, Xiangqian;  Jiang, Bo;  Shi, Dayong
Adobe PDF(8824Kb)  |  收藏  |  浏览/下载：345/0  |  提交时间：2019/08/28
Cu(II)-Catalyzed Oxidative Trifluoromethylation of Indoles with KF as the Base 期刊论文
CATALYSTS, 2019, 卷号: 9, 期号: 3, 页码: 14
作者:  Shi, Xiaolin;  Li, Xiaowei;  Ma, Lina;  Shi, Dayong
Adobe PDF(1208Kb)  |  收藏  |  浏览/下载：316/0  |  提交时间：2019/08/28
Cu(II) catalyst  Langlois reagent  trifluoromethylation  indole  radical reaction  
Halogenated Compounds from Corals: Chemical Diversity and Biological Activities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 15, 页码: 1204-1218
作者:  Zhang, Yuanyuan;  Liu, Junhong;  Shi, Dayong;  Li, Zheng
收藏  |  浏览/下载：127/0  |  提交时间：2020/09/21
Marine  corals  metabolites  halogenated  bioactivity  chemical diversity