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中国科学院海洋研究所机构知识库
Knowledge Management System Of Institute of Oceanology, Chinese Academy of Sciences
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Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
Authors:
Wang, Jun
;
Wang, Lijun
;
Zhang, Shuhong
;
Fan, Junting
;
Yang, Hui
;
Li, Qiqi
;
Guo, Chuanlong
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View/Download:11/0
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Submit date:2020/10/26
eIF4E/eIF4G
Human lung cancer
Apoptosis
DNA damage
ROS
卤代噻唑胺基类化合物的抗三阴性乳腺癌活性研究
学位论文
工学硕士学位, 中国科学院海洋研究所: 中国科学院大学, 2020
Authors:
张佳佳
Adobe PDF(1995Kb)
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View/Download:22/0
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Submit date:2020/06/11
卤代噻唑
抗肿瘤
三阴性乳腺癌
Mda-mb-231
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
Authors:
Guo, Chuanlong
;
Hou, Yuzhen
;
Yu, Xuemin
;
Zhang, Fan
;
Wu, Xiaochen
;
Wu, Xianggen
;
Wang, Lijun
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View/Download:2/0
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Submit date:2020/09/22
Apoptosis
eIF4F
ERK
MNK
A549 cells
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
Authors:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
;
Xu, Kuo
;
Jiang, Bo
;
Jia, Xiaoling
;
Li, Chao
;
Shi, Dayong
Adobe PDF(4835Kb)
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Submit date:2019/08/29
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional agents
eIF4E/eIF4G interaction
Autophagy
ROS
海洋溴酚化合物抗肿瘤活性筛选及作用机制研究
学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2019
Authors:
郭传龙
Adobe PDF(9521Kb)
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View/Download:73/0
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Submit date:2019/06/17
海洋溴酚化合物
抗肿瘤
Eif4e
Parp-1抑制剂