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Halogenated Compounds from Corals: Chemical Diversity and Biological Activities
Zhang, Yuanyuan1; Liu, Junhong1; Shi, Dayong2,3; Li, Zheng1
2019
发表期刊MINI-REVIEWS IN MEDICINAL CHEMISTRY
ISSN1389-5575
卷号19期号:15页码:1204-1218
通讯作者Liu, Junhong(liujh@qust.edu.cn) ; Shi, Dayong(shidayong@qdio.ac.cn)
摘要As important marine biological resources, corals produce a large amount of active organic compounds in their secondary metabolic processes, including numerous brominated, chlorinated, and iodinated compounds. These compounds, with novel structures and unique activities, guide the discovery and research of important lead compounds and novel biological mechanisms. Through a large number of literature surveys, this paper summarized a total of 145 halogenated secondary metabolites which were roughly divided into four major classes of terpenes, prostaglandins, steroids and alkaloids, and they were mainly isolated from ten coral families, Ellisellidae, Gorgoniidae, Briareidae, Plexauridae, Anthothelidae, Alcyoniidae, Clavularidae, Tubiporidae, Nephtheidae and Dendrophyllidae to the best of our knowledge. In addition, their organism species, structure composition and biological activity were also discussed in the form of a chart in this essay.
关键词Marine corals metabolites halogenated bioactivity chemical diversity
DOI10.2174/1389557518666181113124015
收录类别SCI
语种英语
资助项目National Natural Science Foundation of China[81773586] ; National Natural Science Foundation of China[81703354] ; Key research and development project of Shandong province[2016GSF201193] ; Key research and development project of Shandong province[2016ZDJS07A13] ; Key research and development project of Shandong province[2016GSF115002] ; Key research and development project of Shandong province[2016GSF115009] ; CAS[QYZDB-SSW-DQC014] ; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences[ZSTH026] ; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722] ; National Program for Support of Top-notch Young Professionals ; Taishan scholar Youth Project of Shandong province
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal
WOS记录号WOS:000493818600002
出版者BENTHAM SCIENCE PUBL LTD
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/164827
专题实验海洋生物学重点实验室
通讯作者Liu, Junhong; Shi, Dayong
作者单位1.Qingdao Univ Sci & Technol, Dept Pharmaceut, Qingdao 266042, Shandong, Peoples R China
2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China
通讯作者单位中国科学院海洋研究所
推荐引用方式
GB/T 7714
Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,et al. Halogenated Compounds from Corals: Chemical Diversity and Biological Activities[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2019,19(15):1204-1218.
APA Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,&Li, Zheng.(2019).Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.MINI-REVIEWS IN MEDICINAL CHEMISTRY,19(15),1204-1218.
MLA Zhang, Yuanyuan,et al."Halogenated Compounds from Corals: Chemical Diversity and Biological Activities".MINI-REVIEWS IN MEDICINAL CHEMISTRY 19.15(2019):1204-1218.
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