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Comparative Transcriptome Analysis Reveals the Adaptation Mechanism to High Salinity in Litopenaeus vannamei 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 14
作者:  Luo, Zheng;  Yu, Yang;  Zhang, Qian;  Bao, Zhenning;  Xiang, Jianhai;  Li, Fuhua
Adobe PDF(7031Kb)  |  收藏  |  浏览/下载：215/0  |  提交时间：2022/07/18
high-salinity  comparative transcriptome  tolerant families  susceptible families  Litopenaeus vannamei  
Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 卷号: 297, 期号: 4, 页码: 12
作者:  Liu, Ge;  Liu, Rui;  Shan, Yeqi;  Sun, Chaomin
Adobe PDF(3926Kb)  |  收藏  |  浏览/下载：198/0  |  提交时间：2022/01/05
Cytokines Induced by Edwardsiella tarda: Profile and Role in Antibacterial Immunity 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 8, 页码: 16
作者:  Li, Huili;  Sun, Boguang;  Jiang, Shuai;  Sun, Li
Adobe PDF(3779Kb)  |  收藏  |  浏览/下载：235/0  |  提交时间：2021/11/30
cytokine  Edwardsiella tarda  infection  antibody array  immune response  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：206/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Megalocytivirus Induces Complicated Fish Immune Response at Multiple RNA Levels Involving mRNA, miRNA, and circRNA 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 6, 页码: 20
作者:  Wu, Qian;  Ning, Xianhui;  Sun, Li
Adobe PDF(2356Kb)  |  收藏  |  浏览/下载：266/0  |  提交时间：2021/06/04
Paralichthys olivaceus  megalocytivirus  miRNA  ceRNA  immune response  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：331/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：194/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：337/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder-Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 20, 页码: 18
作者:  Li, Wenrui;  Guan, Xiaolu;  Sun, Li
Adobe PDF(3489Kb)  |  收藏  |  浏览/下载：175/0  |  提交时间：2021/04/12
Paralichthys olivaceus  microRNA  phosphatase and tensin homolog  pathogen infection  immune defense  autophagy  apoptosis  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：225/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis