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Proteoglycan from Bacillus sp. BS11 Inhibits the Inflammatory Response by Suppressing the MAPK and NF-kappa B Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 12, 页码: 16
作者:  Wang, Qingchi;  Liu, Weixiang;  Yue, Yang;  Sun, Chaomin;  Zhang, Quanbin
Adobe PDF(2652Kb)  |  收藏  |  浏览/下载：253/0  |  提交时间：2021/04/12
Bacillus sp  proteoglycan  anti-inflammation  macrophages  
Structural and Functional Insights into Iturin W, a Novel Lipopeptide Produced by the Deep-Sea Bacterium Bacillus sp. Strain wsm-1 期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2020, 卷号: 86, 期号: 21, 页码: 12
作者:  Zhou, Shengnan;  Liu, Ge;  Zheng, Rikuan;  Sun, Chaomin;  Wu, Shimei
Adobe PDF(2520Kb)  |  收藏  |  浏览/下载：196/0  |  提交时间：2021/04/12
Bacillus  biocontrol  antifungal  lipopeptide  iturin  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  收藏  |  浏览/下载：226/0  |  提交时间：2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
Optimization of Oyster (Crassostrea talienwhanensis) Protein Hydrolysates Using Response Surface Methodology 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 14
作者:  Wang, Xueqin;  Yu, Huahua;  Xing, Ronge;  Liu, Song;  Chen, Xiaolin;  Li, Pengcheng
Adobe PDF(1389Kb)  |  收藏  |  浏览/下载：269/0  |  提交时间：2020/09/25
oyster  protein hydrolysate  response surface methodology  degree of hydrolysis  hydroxyl-radical-scavenging activity  branched-chain amino acids  
Protective Effect of a Fucose-Rich Fucoidan Isolated fromSaccharina japonicaagainst Ultraviolet B-Induced Photodamage In Vitro in Human Keratinocytes and In Vivo in Zebrafish 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 6, 页码: 12
作者:  Su, Wanchun;  Wang, Lei;  Fu, Xiaoting;  Ni, Liying;  Duan, Delin;  Xu, Jiachao;  Gao, Xin
Adobe PDF(2181Kb)  |  收藏  |  浏览/下载：220/0  |  提交时间：2020/09/25
ROS  Phaeophyta  carbohydrate  UVB irradiation  HaCaT cells  zebrafish  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：222/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载：189/0  |  提交时间：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
Full-length transcriptome sequencing and comparative transcriptomic analysis of different developmental stages of the sporophyll in Undaria pinnatifida (Laminariales: Alariaceae) 期刊论文
JOURNAL OF APPLIED PHYCOLOGY, 2020, 页码: 12
作者:  Shan, Tifeng;  Li, Qianxi;  Wang, Xuemei;  Pang, Shaojun
Adobe PDF(809Kb)  |  收藏  |  浏览/下载：221/0  |  提交时间：2020/09/22
Phaeophyceae  SMRT sequencing  Sporophyll development  Flagellum  Fucoidan  Meiotic nuclear division  
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
作者:  Guo, Chuanlong;  Hou, Yuzhen;  Yu, Xuemin;  Zhang, Fan;  Wu, Xiaochen;  Wu, Xianggen;  Wang, Lijun
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载：197/0  |  提交时间：2020/09/22
Apoptosis  eIF4F  ERK  MNK  A549 cells  
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:  Zhang, Jiajia;  Dai, Jiajia;  Zheng, Qingxuan;  Guo, Shuju;  Yu, Yanyan;  Hu, Wenpeng;  Gao, Yanan;  Shi, Dayong
Adobe PDF(2858Kb)  |  收藏  |  浏览/下载：182/0  |  提交时间：2020/09/23
triple negative breast cancer  MDA-MB-231 cells  fluoro-thiazolylhydrazone  MAPK pathway  phosphorylated p44/42 MAPK (ERK1/2)  phosphorylated c-Jun N-terminal kinase (p-JNK)  apoptosis