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Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载：287/0  |  提交时间：2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
Chrodrimanins O-S from the fungus Penicillium. sp SCS-KFD09 isolated from a marine worm, Sipunculusnudus 期刊论文
FITOTERAPIA, 2017, 卷号: 122, 页码: 1-6
作者:  Kong, Fan-Dong;  Zhang, Ren-Shuai;  Ma, Qing-Yun;  Xie, Qing-Yi;  Wang, Pei;  Chen, Peng-Wei;  Zhou, Li-Man;  Dai, Hao-Fu;  Luo, Du-Qiang;  Zhao, You-Xing
Adobe PDF(681Kb)  |  收藏  |  浏览/下载：259/0  |  提交时间：2018/01/11
Penicillitun Sp.  Chrodrimanins  Fungus  Protein Tyrosine Phosphatase 1b Inhibition  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：345/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载：312/0  |  提交时间：2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：261/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
水母毒素酶类成分鉴定、生物活性及其抑制剂研究 学位论文
, 北京: 中国科学院大学, 2017
作者:  岳洋
Adobe PDF(15950Kb)  |  收藏  |  浏览/下载：628/0  |  提交时间：2017/06/01
水母毒素  酶活性  金属蛋白酶  磷脂酶a2  酶抑制剂  
Functional Elucidation of Nemopilema nomurai and Cyanea nozakii Nematocyst Venoms' Lytic Activity Using Mass Spectrometry and Zymography 期刊论文
TOXINS, 2017, 卷号: 9, 期号: 2
作者:  Yue, Yang;  Yu, Huahua;  Li, Rongfeng;  Xing, Ronge;  Liu, Song;  Li, Kecheng;  Wang, Xueqin;  Chen, Xiaolin;  Li, Pengcheng
Adobe PDF(5507Kb)  |  收藏  |  浏览/下载：251/0  |  提交时间：2017/07/05
Zymography  Lc-ms/ms  Enzymatic Toxins  Hemolysis  Jellyfish Metalloproteinase Inhibitors  Pla(2) Inhibitors  Nemopilema Nomurai  Cyanea Nozakii  
DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis 期刊论文
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2017, 卷号: 61, 期号: 6-7, 页码: 459-463
作者:  Sun, Wei;  Jiao, Shuang;  Tan, Xungang;  Zhang, Peijun;  You, Feng
Adobe PDF(3439Kb)  |  收藏  |  浏览/下载：264/0  |  提交时间：2018/01/11
Zebrafish  Dyrk2  In Situ Hybridization  Muscle Development