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Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:  Deng, Zhenzhen;  Wu, Ning;  Suo, Qishan;  Wang, Jing;  Yue, Yang;  Geng, Lihua;  Zhang, Quanbin
Adobe PDF(8782Kb)  |  收藏  |  浏览/下载：146/0  |  提交时间：2023/01/04
Capecitabine  Tumor microenvironment  Macrophages  TLR4  Fucoidan  
Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 184, 页码: 821-830
作者:  Wang, Fang;  Liu, Changshui;  Wang, Chongyang;  Wang, Yan;  Zang, Kun;  Wang, Xin;  Liu, Xiaohua;  Li, Shihao;  Li, Fuhua;  Ma, Qingjun
Adobe PDF(2684Kb)  |  收藏  |  浏览/下载：217/0  |  提交时间：2021/09/18
Stl dUTPase interactions  Proteinaceous inhibitor  Crystal structure  
A combined analysis of transcriptomics and proteomics of a novel Antarctic Salpa sp. and its potential toxin screenings 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 1101-1113
作者:  Ye, Ruiwei;  Liang, Hongyu;  Chen, Ting;  Zhang, Jie;  Yang, Fengling;  Chen, Xintong;  Li, Xiaoya;  Gao, Songyu;  Yang, Ying;  Wang, Yongqiang;  Tao, Feng;  Zhang, Jing;  Xiao, Liang
Adobe PDF(6067Kb)  |  收藏  |  浏览/下载：211/0  |  提交时间：2020/10/26
Antarctic  Salpa  Transcriptome  Proteome  Toxin  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  收藏  |  浏览/下载：203/0  |  提交时间：2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
Integrated proteomics and metabolomics analysis reveals the antifungal mechanism of the C-coordinated O-carboxymethyl chitosan Cu (II) complex 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 155, 页码: 1491-1509
作者:  Ma, Yuzhen;  Yu, Huahua;  Liu, Weixiang;  Qin, Yukun;  Xing, Ronge;  Li, Pengcheng
Adobe PDF(13837Kb)  |  收藏  |  浏览/下载：220/0  |  提交时间：2020/09/24
Natural organic-based copper  O-CSLn-Cu  Phytophthora capsici Leonian  Proteomics-metabonomics integrated analysis  Antifungal mechanism  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：197/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
H-1 NMR characterization of chitin tetrasaccharide in binary H2O:DMSO solution: Evidence for anomeric end-effect propagation 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 129, 页码: 744-749
作者:  Li, Kecheng;  Green, Andrew R.;  Dinges, Meredith M.;  Larive, Cynthia K.
Adobe PDF(818Kb)  |  收藏  |  浏览/下载：301/0  |  提交时间：2019/08/28
Chitin  Structure characterization  Amide proton  Binary solvent  End-effect  
Vascular targeted chitosan-derived nanoparticles as docetaxel carriers for gastric cancer therapy 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 126, 页码: 662-672
作者:  Zhang, Enhui;  Xing, Ronge;  Liu, Song;  Li, Kecheng;  Qin, Yukun;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2790Kb)  |  收藏  |  浏览/下载：236/0  |  提交时间：2019/05/15
Targeted drug delivery  Chitosan  Docetaxel  
Glucofucogalactan, a heterogeneous low-sulfated polysaccharide from Saccharina japonica and its bioactivity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 90-97
作者:  Geng, Lihua;  Zhang, Quanbin;  Wang, Jing;  Jin, Weihua;  Zhao, Tingting;  Hu, Weicheng
Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：289/0  |  提交时间：2019/08/21
Saccharina japonica  Heteropolysaccharide  Aristolochic acid  Immunomodulation  
Immunostimulatory effects of sulfated chitosans on RAW 264.7 mouse macrophages via the activation of PI3 K/Akt signaling pathway 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 108, 页码: 1310-1321
作者:  Yang, Yue;  Xing, Ronge;  Liu, Song;  Qin, Yukun;  Li, Kecheng;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2800Kb)  |  收藏  |  浏览/下载：304/0  |  提交时间：2019/08/21
Sulfated chitosan  Immunostimulatory activity  Nuclear factor-kappa B  Toll like receptor-4