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A heteropolysaccharide from Saccharina japonica with immunomodulatory effect on RAW 264.7 cells 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 557-565
作者:  Geng, Lihua;  Hu, Weicheng;  Liu, Yingjuan;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(2011Kb)  |  收藏  |  浏览/下载:270/0  |  提交时间:2019/08/27
Saccharina japonica  Polysaccharide  Immunomodulatory activity  Macrophage  
Mechanistic target of rapamycin inhibition with rapamycin induces autophagy and correlative regulation in white shrimp (Litopenaeus vannamei) 期刊论文
AQUACULTURE NUTRITION, 2018, 卷号: 24, 期号: 5, 页码: 1509-1520
作者:  Liu, Xinwei;  Wang, Mengqiang;  Sun, Guoqiong;  Wang, Baojie;  Jiang, Keyong;  Shao, Jianchun;  Qi, Cancan;  Zhao, Wei;  Han, Siyin;  Liu, Mei;  Wang, Lei
Adobe PDF(1148Kb)  |  收藏  |  浏览/下载:356/0  |  提交时间:2019/08/26
autophagy  Litopenaeus vannamei  mTOR  rapamycin  transcriptome  
The effect of different substitute groups and molecular weights of fucoidan on neuroprotective and anticomplement activity 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 113, 页码: 82-89
作者:  Liu, Huaide;  Wang, Jing;  Zhang, Quanbin;  Zhang, Hong
Adobe PDF(883Kb)  |  收藏  |  浏览/下载:283/0  |  提交时间:2019/08/21
Fucoidan derivatives  Molecular weights  Substitute group  Neuroprotective  Anticomplement  
长牡蛎Toll样受体介导的抗病毒相关基因的功能及调控机制研究 学位论文
农学博士, 中国科学院海洋研究所: 中国科学院大学, 2018
作者:  唐雪颖
Adobe PDF(4869Kb)  |  收藏  |  浏览/下载:314/1  |  提交时间:2018/06/23
长牡蛎  Tlr信号通路  天然免疫  牡蛎疱疹病毒  
CgNrdp1, a conserved negative regulating factor of MyD88-dependent Toll like receptor signaling in oyster Crassostrea gigas 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 页码: 386-392
作者:  Sun, Rui;  Qiu, Limei;  Yi, Qilin;  Wang, Mengqiang;  Yue, Feng;  Wang, Lingling;  Song, Linsheng
Adobe PDF(602Kb)  |  收藏  |  浏览/下载:255/0  |  提交时间:2019/08/21
Nrdp1  Toll like receptor signaling pathway  Immune regulation  Evolution of innate immunity  Crassostrea gigas  
The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 页码: 205-212
作者:  Wang, Mengqiang;  Wang, Lingling;  Jia, Zhihao;  Yi, Qilin;  Song, Linsheng
Adobe PDF(686Kb)  |  收藏  |  浏览/下载:254/0  |  提交时间:2019/08/21
Chlamys farreri  Innate immunity  TLR signaling pathway  
Immunostimulatory effects of sulfated chitosans on RAW 264.7 mouse macrophages via the activation of PI3 K/Akt signaling pathway 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 108, 页码: 1310-1321
作者:  Yang, Yue;  Xing, Ronge;  Liu, Song;  Qin, Yukun;  Li, Kecheng;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(2800Kb)  |  收藏  |  浏览/下载:304/0  |  提交时间:2019/08/21
Sulfated chitosan  Immunostimulatory activity  Nuclear factor-kappa B  Toll like receptor-4  
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Adobe PDF(5208Kb)  |  收藏  |  浏览/下载:320/0  |  提交时间:2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 13
作者:  Yue, Xin;  Huan, Pin;  Hu, Yonghua;  Liu, Baozhong
Adobe PDF(1951Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2019/08/21
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载:226/0  |  提交时间:2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes