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Pelagic ciliate (Ciliophora) communities in the Southern Ocean: Bioindicator to water mass, habitat suitability classification and potential response to global warming 期刊论文
PROGRESS IN OCEANOGRAPHY, 2023, 卷号: 216, 页码: 13
作者:  Wang, Chaofeng;  Wang, Xiaoyu;  Wei, Yuanyuan;  Guo, Guijun;  Li, Haibo;  Wan, Aiyong;  Zhang, Wuchang
收藏  |  浏览/下载：127/0  |  提交时间：2023/12/13
Microzooplankton  Pelagic ciliates  Habitat suitability  Indicator  Southern Ocean  Water mass  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：323/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载：179/0  |  提交时间：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
The Characteristics of Storm Wave Behavior and Its Effect on Cage Culture Using the ADCIRC plus SWAN Model in Houshui Bay, China 期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2020, 卷号: 19, 期号: 2, 页码: 307-319
作者:  Yin, Chao;  Huang, Haijun;  Wang, Daoru;  Liu, Yanxia;  Guo, Ziyue
Adobe PDF(1414Kb)  |  收藏  |  浏览/下载：144/0  |  提交时间：2020/09/21
storm wave  ADCIRC plus SWAN  maximum significant wave height  Houshui Bay  deep sea net-cage  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：329/0  |  提交时间：2020/03/20
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Adobe PDF(4835Kb)  |  收藏  |  浏览/下载：356/0  |  提交时间：2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
收藏  |  浏览/下载：350/0  |  提交时间：2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Geophysical evidence for gas hydrate accumulation related to methane seepage in the Taixinan Basin, South China Sea 期刊论文
JOURNAL OF ASIAN EARTH SCIENCES, 2018, 卷号: 168, 页码: 27-37
作者:  Wang, Xiujuan;  Liu, Bo;  Qian, Jin;  Zhang, Xin;  Guo, Yiqun;  Su, Pibo;  Liang, Jinqiang;  Jin, Jiapeng;  Luan, Zhendong;  Chen, Duanxin;  Xi, Shichuan;  Li, Chaolun
Adobe PDF(3166Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2019/05/15
Methane seepage  Gas hydrate  Free gas  Saturation  Fluid flow  Taixinan Basin  
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
Adobe PDF(824Kb)  |  收藏  |  浏览/下载：303/0  |  提交时间：2019/08/21
Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
The pearl oyster Pinctada fucata martensii genome and multi-omic analyses provide insights into biomineralization 期刊论文
GIGASCIENCE, 2017, 卷号: 6, 期号: 8
作者:  Du, Xiaodong;  Fan, Guangyi;  Jiao, Yu;  Zhang, He;  Guo, Ximing;  Huang, Ronglian;  Zheng, Zhe;  Bian, Chao;  Deng, Yuewen;  Wang, Qingheng;  Wang, Zhongduo;  Liang, Xinming;  Liang, Haiying;  Shi, Chengcheng;  Zhao, Xiaoxia;  Sun, Fengming;  Hao, Ruijuan;  Bai, Jie;  Liu, Jialiang;  Chen, Wenbin;  Liang, Jinlian;  Liu, Weiqing;  Xu, Zhe;  Shi, Qiong;  Xu, Xun;  Zhang, Guofan;  Liu, Xin
Adobe PDF(1968Kb)  |  收藏  |  浏览/下载：484/0  |  提交时间：2018/01/11
Genome  Biomineralization  Nacre  Vwa-containing Protein  Pinctada Fucata Martensii