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Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 806-823
作者:  Wang, Li-Jun;  Wang, Shuai-Yu;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Wang, Bao-Cheng;  Luo, Jiao;  Yang, Meng;  Jin, Shui-Hua;  Shi, Da-Yong
Adobe PDF(1301Kb)  |  收藏  |  浏览/下载：249/0  |  提交时间：2015/06/15
Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 60, 页码: 48822-48834
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(1045Kb)  |  收藏  |  浏览/下载：236/1  |  提交时间：2015/07/27
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载：268/0  |  提交时间：2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao;  Shi, DY
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：326/1  |  提交时间：2014/07/17
Type 2 Diabetes Mellitus  Protein Tyrosine Phosphatase 1b  Bromophenol  Anti-diabetic Activities  
Halogenated Organic Molecules of Rhodomelaceae Origin: Chemistry and Biology 期刊论文
CHEMICAL REVIEWS, 2013, 卷号: 113, 期号: 5, 页码: 3632-3685
作者:  Wang, Bin-Gui;  Gloer, James B.;  Ji, Nai-Yun;  Zhao, Jian-Chun;  Wang, BG
Adobe PDF(9186Kb)  |  收藏  |  浏览/下载：305/0  |  提交时间：2014/07/17
New nitrogen-containing bromophenols from the marine red alga Rhodomela confervoides and their radical scavenging activity 期刊论文
FOOD CHEMISTRY, 2012, 卷号: 135, 期号: 3, 页码: 868-872
作者:  Li, Ke;  Li, Xiao-Ming;  Gloer, James B.;  Wang, Bin-Gui;  Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
Adobe PDF(332Kb)  |  收藏  |  浏览/下载：433/0  |  提交时间：2013/09/24
Marine Red Alga  Rhodomela Confervoides  Bromophenol  Radical Scavenging Activity  
Synthesis and protein tyrosine phosphatase 1B inhibition activities of two new synthetic bromophenols and their methoxy derivatives 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 6, 页码: 1237-1242
作者:  Cui Yongchao;  Shi Dayong;  Hu Zhiqiang
Adobe PDF(413Kb)  |  收藏  |  浏览/下载：256/1  |  提交时间：2012/07/03
Protein Tyrosine Phosphatase 1b Inhibition  Bromophenol Derivatives  Synthesis  
Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 卷号: 59, 期号: 18, 页码: 9916-9921
作者:  Li, Ke;  Li, Xiao-Ming;  Gloer, James B.;  Wang, Bin-Gui
Adobe PDF(757Kb)  |  收藏  |  浏览/下载：398/1  |  提交时间：2012/07/03
Marine Alga  Rhodomela Confervoides  Bromophenol  Radical Scavenging Activity  Dpph  Abts  
Bromophenols in Marine Algae and Their Bioactivities 期刊论文
MARINE DRUGS, 2011, 卷号: 9, 期号: 7, 页码: 1273-1292
作者:  Liu, Ming;  Hansen, Poul Erik;  Lin, Xiukun
Adobe PDF(251Kb)  |  收藏  |  浏览/下载：205/0  |  提交时间：2012/07/03
Bromophenols  Marine Algae  Bioactivity  
一类治疗血栓性心脑血管疾病的药物及其应用 专利
专利类型: 发明, 专利号: CN201010147850.6, 申请日期: 2011-04-20, 公开日期: 2011-04-20
发明人:  史大永;  范晓;  卢伟伸;  郭书举;  崔永超
Adobe PDF(1195Kb)  |  收藏  |  浏览/下载：260/0  |  提交时间：2014/08/04
一类治疗血栓性心脑血管疾病的药物  具有如下结构化合物、以及它们药学上可接受的衍生物中的一种或一种以上为活性成份：化合物i：中文名称：(2′  英文名称：(2′  3′?二溴?4′  3′?dibromo?4′  化合物ii：中文名称：双?(2  5′?二羟基?苯基)?(2  5′?dihydroxy?phenyl)?(2  3  英文名称：bis?(2  3  3  6?三溴?4  3  化合物iii：中文名称：双?(2  6?三溴?4  6?tribromo?4  5?二羟基?苯基)?甲酮  6?tribromo?4  3?二溴?4  英文名称：bis?(2  5?二羟基?苯基)?甲酮  5?dihydroxy?phenyl)?methanone  5?dihydroxy?phenyl)?methanone  5?二羟基苯基)?甲烷  3?dibromo?4  化合物iv：中文名称：双?(2  5?dihydroxy?phenyl)?methane  3  英文名称：bis?(2  6?三溴?4  3  化合物v：中文名称：(2′  5?二羟基?苯基)?甲烷  6?tribromo?4  3′?二溴?4′  英文名称：(2′  5?dihydroxy?phenyl)?methane  5′?二羟基?苯基)?(2  3′?dibromo?4′  化合物vi：中文名称：3  3  5′?dihydroxy?phenyl)?(2  4?二溴?5?(2′?溴?3′  英文名称：3  6?三溴?4  3  4′?二羟基?6′?乙氧甲基苄基)?苯?1  4?dibromo?5?(2′?bromo?3′  化合物vii：中文名称：3  5?二羟基?苯基)?甲烷  6?tribromo?4  2?二醇  4′?dihydroxy?6′?ethoxymethyl?benzyl)?benzene?1  4?二溴?5?(2′?溴?3′  英文名称：3  5?dihydroxy?phenyl)?methane  2?diol  4′?二羟基?6′?甲氧甲基苄基)?苯?1  4?dibromo?5?(2′?bromo?3′  2?二醇  4′?dihydroxy?6′?methoxymethyl?benzyl)?benzene?1  2?diol。fsa00000065600900011.tif