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A new steroid with potent antimicrobial activities and two new polyketides from Penicillium variabile EN-394, a fungus obtained from the marine red alga Rhodomela confervoides 期刊论文
JOURNAL OF ANTIBIOTICS, 2023, 页码: 8
作者:  Zhang, Fan-Zhong;  Li, Xiao-Ming;  Meng, Ling-Hong;  Wang, Bin-Gui
收藏  |  浏览/下载：71/0  |  提交时间：2023/11/30
两株深海来源真菌CS-793与AS-130中萜类天然产物的挖掘与应用评价 学位论文
工学硕士, 中科院海洋研究所: 中国科学院大学, 2023
作者:  英振
Adobe PDF(10661Kb)  |  收藏  |  浏览/下载：65/1  |  提交时间：2023/06/14
海洋微生物  深海真菌  次级代谢产物研  萜类化合物  生物活性  
Cyclopiumolides A and B, unusual 13-membered macrolides from the deep sea-sourced fungus Penicillium cyclopium SD-413 with antiproliferative activities 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:  Li, Yan-He;  Yang, Sui-Qun;  Li, Xiao-Ming;  Li, Xin;  Wang, Bin-Gui;  Li, Hong-Lei
Adobe PDF(3286Kb)  |  收藏  |  浏览/下载：179/0  |  提交时间：2023/01/06
Macrolides  Penicillium cyclopium  Deep-sea sediment  Cytotoxicity  
Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa 期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 3, 页码: 11
作者:  Wang, Ying;  Li, Xiao-Ming;  Yang, Sui-Qun;  Zhang, Fan-Zhong;  Wang, Bin-Gui;  Li, Hong-Lei;  Meng, Ling-Hong
Adobe PDF(2093Kb)  |  收藏  |  浏览/下载：224/0  |  提交时间：2022/07/15
Trichoderma longibrachiatum  sesquiterpene glycoside  secondary metabolites  antimicrobial activity  
Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides 期刊论文
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2021, 卷号: 56, 页码: 5
作者:  Li, Ke;  Li, Xiao-Ming;  Gloer, James B.;  Wang, Bin-Gui
Adobe PDF(541Kb)  |  收藏  |  浏览/下载：136/0  |  提交时间：2021/12/07
Marine red alga  Rhodomela confervoides  Ureidobromophenols  Antioxidant activity  
海洋溴酚化合物对肠道菌群的调节与益生菌降糖作用研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2021
作者:  张良
Adobe PDF(5745Kb)  |  收藏  |  浏览/下载：184/0  |  提交时间：2021/06/17
海洋溴酚化合物，肠道微生物，菌群结构，益生特性，降糖作用  
Structurally diverse alkaloids produced by Aspergillus creber EN-602, an endophytic fungus obtained from the marine red alga Rhodomela confervoides 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 8
作者:  Li, Hong-Lei;  Yang, Sui-Qun;  Li, Xiao-Ming;  Li, Xin;  Wang, Bin-Gui
Adobe PDF(2714Kb)  |  收藏  |  浏览/下载：254/0  |  提交时间：2021/06/24
Diketopiperazine  Aspergillus creber  Rhodomela confervoides  Endophytic fungus  ACE inhibitory activity  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：191/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：163/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability