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| New nitrogen-containing bromophenols from the marine red alga Rhodomela confervoides and their radical scavenging activity | |
Li, Ke1; Li, Xiao-Ming1; Gloer, James B.2; Wang, Bin-Gui1 ; Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
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| 2012-12-01 | |
| 发表期刊 | FOOD CHEMISTRY
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| ISSN | 0308-8146 |
| 卷号 | 135期号:3页码:868-872 |
| 文章类型 | Article |
| 摘要 | In addition to nine known bromophenol derivatives, five new nitrogen-containing bromophenols were isolated from an ethyl acetate extract of the marine red alga Rhodomela confervoides. By using spectro-scopic methods, the structures of the new compounds were identified as 3-(2,3-dibromo-4,5-dihydroxybenzyl)pyrrolidine-2,5-dione (1), methyl 4-(2,3-dibromo-4,5-dihydroxybenzylamino)-4-oxobutanoate (2), 4-(2,3-dibromo-4,5-dihydroxybenzylamino)-4-oxobutanoic acid (3), 3-bromo-5-hydroxy-4-methoxybenzamide (4), and 2-(3-bromo-5-hydroxy-4-methoxyphenyl)acetamide (5). All of these bromophenols showed potent scavenging activity against DPPH (1,1-diphenyl-2-picrylhydrazyl) radicals, with IC50 values ranging from 5.22 to 23.60 mu M. These compounds also displayed moderate activity against ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonate) radicals, with Trolox Equivalent Antioxidant Capacity values (TEAC) ranging from 2.11 to 3.58 mM. The results obtained in this study demonstrate that the bromophenols obtained from R. confervoides may have potential application in food and/or pharmaceutical fields as natural antioxidants. (C) 2012 Elsevier Ltd. All rights reserved. |
| 关键词 | Marine Red Alga Rhodomela Confervoides Bromophenol Radical Scavenging Activity |
| 学科领域 | Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics |
| DOI | 10.1016/j.foodchem.2012.05.117 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310396700002 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12366 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Iowa, Dept Chem, Iowa City, IA 52242 USA |
| 第一作者单位 | 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | Li, Ke,Li, Xiao-Ming,Gloer, James B.,et al. New nitrogen-containing bromophenols from the marine red alga Rhodomela confervoides and their radical scavenging activity[J]. FOOD CHEMISTRY,2012,135(3):868-872. |
| APA | Li, Ke,Li, Xiao-Ming,Gloer, James B.,Wang, Bin-Gui,&Wang, BG .(2012).New nitrogen-containing bromophenols from the marine red alga Rhodomela confervoides and their radical scavenging activity.FOOD CHEMISTRY,135(3),868-872. |
| MLA | Li, Ke,et al."New nitrogen-containing bromophenols from the marine red alga Rhodomela confervoides and their radical scavenging activity".FOOD CHEMISTRY 135.3(2012):868-872. |
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