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Low molecular weight fucoidan fraction LF2 improves metabolic syndrome via up-regulating PI3K-AKT-mTOR axis and increasing the abundance of Akkermansia muciniphila in the gut microbiota 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 193, 页码: 789-798
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wang, Fahe;  Zhang, Quanbin
Adobe PDF(3607Kb)  |  收藏  |  浏览/下载：201/0  |  提交时间：2022/02/18
Fucoidan  Metabolic syndrome  Gut microbiota  
Dietary fibers extracted from Saccharina japonica can improve metabolic syndrome and ameliorate gut microbiota dysbiosis induced by high fat diet 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2021, 卷号: 85, 页码: 11
作者:  Deng, Zhenzhen;  Wu, Ning;  Wang, Jing;  Zhang, Quanbin
Adobe PDF(5410Kb)  |  收藏  |  浏览/下载：205/0  |  提交时间：2021/11/30
Dietary fiber  Insulin resistance  Metabolic syndrome  Gut microbiota  
Degradation of different molecular weight fucoidans and their inhibition of TGF-beta 1 induced epithelial-mesenchymal transition in mouse renal tubular epithelial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 151, 页码: 545-553
作者:  Li, Xiaosong;  Wu, Ning;  Chen, Yongqiang;  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Qin, Yimin;  Zhang, Quanbin
Adobe PDF(2869Kb)  |  收藏  |  浏览/下载：205/0  |  提交时间：2020/09/23
Degradation  Fucoidan  Epithelial-mesenchymal transition  Kidney fibrosis  
Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 304-314
作者:  Wang, Jing;  Zhang, Quanbin;  Li, Shuang;  Chen, Zhihang;  Tan, Jiaojiao;  Yao, Jianting;  Duan, Delin
Adobe PDF(2307Kb)  |  收藏  |  浏览/下载：178/0  |  提交时间：2020/09/23
Fucoidan  ECM-receptor interaction  Fibronectin  
Comparative Study of Fucoidan from Saccharina japonica and Its Depolymerized Fragment on Adriamycin-Induced Nephrotic Syndrome in Rats 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 3, 页码: 10
作者:  Tan, Jiaojiao;  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Wu, Ning;  Zhang, Quanbin
Adobe PDF(401Kb)  |  收藏  |  浏览/下载：211/0  |  提交时间：2020/09/23
fucoidan  low-molecular-weight fucoidan  adriamycin  nephrotic syndrome  
Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies 期刊论文
GLYCANS AND GLYCOSAMINOGLYCANS AS CLINICAL BIOMARKERS AND THERAPEUTICS, PT B, 2019, 卷号: 163, 页码: 95-111
作者:  Wang, Jing;  Geng, Lihua;  Yue, Yang;  Zhang, Quanbin
Adobe PDF(399Kb)  |  收藏  |  浏览/下载：244/0  |  提交时间：2020/01/03
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs) 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
作者:  Deng, Zhenzhen;  Liu, Yingjuan;  Wang, Jing;  Wu, Suhuang;  Geng, Lihua;  Sui, Zhenghong;  Zhang, Quanbin
Adobe PDF(2987Kb)  |  收藏  |  浏览/下载：316/0  |  提交时间：2019/08/27
Gracilariopsis lemaneiformis  ACE-inhibitory activity  peptide  molecular docking  SHRs  
Low molecular weight fucoidan ameliorates streptozotocin-induced hyper-responsiveness of aortic smooth muscles in type 1 diabetes rats 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 191, 页码: 341-349
作者:  Liang, Zhengyang;  Zheng, Yuanyuan;  Wang, Jing;  Zhang, Quanbin;  Ren, Shuang;  Liu, Tiantian;  Wang, Zhiqiang;  Luo, Dali
Adobe PDF(1478Kb)  |  收藏  |  浏览/下载：295/1  |  提交时间：2017/03/21
Fucoidan  Diabetes  Vascular Smooth Muscles  Aorta  Hypertension  
The Protective Effect of Fucoidan in Rats with Streptozotocin-Induced Diabetic Nephropathy 期刊论文
MARINE DRUGS, 2014, 卷号: 12, 期号: 6, 页码: 3292-3306
作者:  Wang, Jing;  Liu, Huaide;  Li, Ning;  Zhang, Quanbin;  Zhang, Hong;  Li, N (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(1554Kb)  |  收藏  |  浏览/下载：242/1  |  提交时间：2015/06/11
Sulfated Polysaccharide  Fucoidan  Diabetic Nephropathy  
Low-molecular-weight fucoidan protects endothelial function and ameliorates basal hypertension in diabetic Goto-Kakizaki rats 期刊论文
LABORATORY INVESTIGATION, 2014, 卷号: 94, 期号: 4, 页码: 382-393
作者:  Cui, Wentong;  Zheng, Yuanyuan;  Zhang, Quanbin;  Wang, Jing;  Wang, Limin;  Yang, Wenzhe;  Guo, Chenyang;  Gao, Weidong;  Wang, Xiaomin;  Luo, Dali;  Luo, DL (reprint author), Capital Med Univ, Dept Pharmacol, St Youanmenwai,10 Xitoutiao, Beijing 100069, Peoples R China.
Adobe PDF(473Kb)  |  收藏  |  浏览/下载：272/0  |  提交时间：2015/06/11
Diabetes  Endothelium-dependent Vasodilation  Endothelial Nitric Oxide Synthase  Low-molecular-weight Fucoidan  Nitric Oxide