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Structural Characterization of Gracilariopsis lemaneiformis Polysaccharide and Its Property in Delaying Cellular Senescence 期刊论文
FRONTIERS IN NUTRITION, 2022, 卷号: 9, 页码: 12
作者:  Wang, Xiaomei;  Xu, Xiaogang;  Mao, Genxiang;  Guo, Yue;  Wang, Guangce;  Sun, Xue;  Xu, Nianjun;  Zhang, Zhongshan
Adobe PDF(3812Kb)  |  收藏  |  浏览/下载:182/0  |  提交时间:2022/07/18
G. lemaneiformis  polysaccharide  cellular senescence  SA-beta-gal  p53-p21 pathway  
Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 卷号: 297, 期号: 4, 页码: 12
作者:  Liu, Ge;  Liu, Rui;  Shan, Yeqi;  Sun, Chaomin
Adobe PDF(3926Kb)  |  收藏  |  浏览/下载:200/0  |  提交时间:2022/01/05
Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides 期刊论文
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2021, 卷号: 56, 页码: 5
作者:  Li, Ke;  Li, Xiao-Ming;  Gloer, James B.;  Wang, Bin-Gui
Adobe PDF(541Kb)  |  收藏  |  浏览/下载:165/0  |  提交时间:2021/12/07
Marine red alga  Rhodomela confervoides  Ureidobromophenols  Antioxidant activity  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载:208/0  |  提交时间:2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Review: Advances in preparation of chitooligosaccharides with heterogeneous sequences and their bioactivity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 252, 页码: 11
作者:  Hao, Wentong;  Li, Kecheng;  Li, Pengcheng
Adobe PDF(3003Kb)  |  收藏  |  浏览/下载:237/0  |  提交时间:2021/04/12
Chitooligosaccharides  Heterogeneous sequences  Chitin deacetylases  Synthesis  Preparation  
Immunostimulatory effect of N-2-hydroxypropyltrimethyl ammonium chloride chitosan-sulfate chitosan complex nanoparticles on dendritic cells 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 251, 页码: 11
作者:  Xu, Chaojie;  Xing, Ronge;  Liu, Song;  Qin, Yukun;  Li, Kecheng;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(4834Kb)  |  收藏  |  浏览/下载:285/0  |  提交时间:2021/04/12
Chitosan quaternary ammonium salt  Sulfated chitosan  Nanoparticles  DCS cells  Immunostimulatory activities  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载:197/0  |  提交时间:2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:341/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei 期刊论文
MARINE BIOTECHNOLOGY, 2020, 卷号: 22, 期号: 4, 页码: 564-571
作者:  Wang, Quanchao;  Yu, Yang;  Zhang, Qian;  Luo, Zheng;  Zhang, Xiaojun;  Xiang, Jianhai;  Li, Fuhua
Adobe PDF(712Kb)  |  收藏  |  浏览/下载:294/0  |  提交时间:2020/09/25
Penaeid shrimp  Growth traits  GWAS  Candidate gene  MMD2  
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:  Zhang, Jiajia;  Dai, Jiajia;  Zheng, Qingxuan;  Guo, Shuju;  Yu, Yanyan;  Hu, Wenpeng;  Gao, Yanan;  Shi, Dayong
Adobe PDF(2858Kb)  |  收藏  |  浏览/下载:187/0  |  提交时间:2020/09/23
triple negative breast cancer  MDA-MB-231 cells  fluoro-thiazolylhydrazone  MAPK pathway  phosphorylated p44/42 MAPK (ERK1/2)  phosphorylated c-Jun N-terminal kinase (p-JNK)  apoptosis