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Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：178/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：323/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder-Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 20, 页码: 18
作者:  Li, Wenrui;  Guan, Xiaolu;  Sun, Li
Adobe PDF(3489Kb)  |  收藏  |  浏览/下载：165/0  |  提交时间：2021/04/12
Paralichthys olivaceus  microRNA  phosphatase and tensin homolog  pathogen infection  immune defense  autophagy  apoptosis  
In vitro and in vivo anti-inflammatory activities of a fucose-rich fucoidan isolated from Saccharina japonica 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 156, 页码: 717-729
作者:  Ni, Liying;  Wang, Lei;  Fu, Xiaoting;  Duan, Delin;  Jeon, You-Jin;  Xu, Jiachao;  Gao, Xin
Adobe PDF(2376Kb)  |  收藏  |  浏览/下载：174/0  |  提交时间：2020/09/25
Saccharine japonica  Fucoidan  Structure  Anti-inflammation  RAW 264.7  Zebrafish  
Integrated proteomics and metabolomics analysis reveals the antifungal mechanism of the C-coordinated O-carboxymethyl chitosan Cu (II) complex 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 155, 页码: 1491-1509
作者:  Ma, Yuzhen;  Yu, Huahua;  Liu, Weixiang;  Qin, Yukun;  Xing, Ronge;  Li, Pengcheng
Adobe PDF(13837Kb)  |  收藏  |  浏览/下载：241/0  |  提交时间：2020/09/24
Natural organic-based copper  O-CSLn-Cu  Phytophthora capsici Leonian  Proteomics-metabonomics integrated analysis  Antifungal mechanism  
An insulin-like peptide serves as a regulator of glucose metabolism in the immune response of Chinese mitten crab Eriocheir sinensis 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 卷号: 108, 页码: 9
作者:  Wang, Lin;  Chen, Hao;  Wang, Lingling;  Song, Linsheng
Adobe PDF(7707Kb)  |  收藏  |  浏览/下载：266/0  |  提交时间：2020/09/23
Aeromonas hydrophila infection  Chinese mitten crab  Glucose metabolism  Insulin-like peptide  Immune response  
Genome-wide analysis of the Saccharina japonica sulfotransferase genes and their transcriptional profiles during whole developmental periods and under abiotic stresses 期刊论文
BMC PLANT BIOLOGY, 2020, 卷号: 20, 期号: 1, 页码: 20
作者:  Lu, Chang;  Shao, Zhanru;  Zhang, Pengyan;  Duan, Delin
Adobe PDF(3107Kb)  |  收藏  |  浏览/下载：171/0  |  提交时间：2020/09/25
Saccharina japonica  Sulfotransferase  Fucoidan  Transcriptome  Genome  
长牡蛎糖原含量多组学机制及关键基因功能研究 学位论文
理学博士学位, 中国科学院海洋研究所: 中国科学院大学, 2020
作者:  李步苏
Adobe PDF(5467Kb)  |  收藏  |  浏览/下载：690/1  |  提交时间：2020/06/11
长牡蛎  糖原  生糖蛋白  游离脂肪酸受体4  
海带低分子量褐藻多糖硫酸酯对糖尿病肾病的作用机制研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
作者:  王菁
Adobe PDF(4674Kb)  |  收藏  |  浏览/下载：1140/1  |  提交时间：2020/06/09
低分子量褐藻多糖硫酸酯  糖尿病肾病  纤维连接蛋白  细胞外基质-受体相互作用  肠道菌群  
Cationic chitosan derivatives as potential antifungals: A review of structural optimization and applications 期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 236, 页码: 17
作者:  Qin, Yukun;  Li, Pengcheng;  Guo, Zhanyong
Adobe PDF(1903Kb)  |  收藏  |  浏览/下载：153/0  |  提交时间：2020/09/22
Cationic chitosan derivatives  Antifungals  Structural optimization strategy  Antifungal therapy