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Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：164/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：303/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
Adobe PDF(2455Kb)  |  收藏  |  浏览/下载：263/0  |  提交时间：2020/09/25
CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Adobe PDF(2321Kb)  |  收藏  |  浏览/下载：198/0  |  提交时间：2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Phytochemical and chemotaxonomic study on Leathesia nana (Chordariaceae) 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2018, 卷号: 81, 页码: 42-44
作者:  Xu, Kuo;  Guo, Shuju;  Jia, Xiaoling;  Li, Xiang;  Shi, Dayong
Adobe PDF(298Kb)  |  收藏  |  浏览/下载：261/0  |  提交时间：2019/05/15
Leathesia nana  Chordariaceae  Bromophenol  Chemotaxonomy  PTP1B  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载：312/0  |  提交时间：2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
新型氟代PTP1B抑制剂的设计、合成及活性研究 学位论文
, 北京: 中国科学院大学, 2016
作者:  王保程
Adobe PDF(4845Kb)  |  收藏  |  浏览/下载：260/0  |  提交时间：2016/05/31
糖尿病  氟代化合物  Ptp1b抑制剂  计算机辅助药物设计  分子对接  
Extraction and PTP1B inhibitory activity of bromophenols from the marine red alga Symphyocladia latiuscula 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 3, 页码: 686-690
作者:  Liu Xu;  Li Xiaoming;  Gao Lixin;  Cui Chuanming;  Li Chunshun;  Li Jia;  Wang Bingui
Adobe PDF(279Kb)  |  收藏  |  浏览/下载：233/0  |  提交时间：2012/07/03
Marine Alga  Rhodomelaceae  Symphyocladia Latiuscula  Bromophenol  Protein Tyrosine Phosphatase 1b (Ptp1b)  
Synthesis of three bromophenols from red algae as PTP1B inhibitors 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 1, 页码: 68-74
作者:  Guo Shuju;  Li Jing;  Li Ting;  Shi Dayong;  Han Lijun
Adobe PDF(360Kb)  |  收藏  |  浏览/下载：370/0  |  提交时间：2012/07/03
Bromophenols  Synthesis  Ptp1b Inhibitory Activity  
蒲枝凹顶藻、鸭毛藻及鸭毛藻共生真菌次生代谢产物研究 学位论文
, 北京: 中国科学院研究生院, 2010
作者:  刘旭
Adobe PDF(3293Kb)  |  收藏  |  浏览/下载：662/3  |  提交时间：2012/06/21
蒲枝凹顶藻  鸭毛藻  哈茨木霉  共生真菌  Ptp1b 抑制剂  抗菌活性