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A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：348/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Characterization and functional analysis of two inhibitor of apoptosis genes in Zhikong scallop Chlamys farreri 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2016, 卷号: 60, 页码: 1-11
作者:  Miao, Guoying;  Qi, Haigang;  Li, Li;  Que, Huayong;  Zhang, Guofan
Adobe PDF(5265Kb)  |  收藏  |  浏览/下载：240/3  |  提交时间：2016/09/19
Zhikong Scallop  Chlamys Farreri  Inhibitor Of Apoptosis  Apoptosis  Innate Immunity  
Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells 期刊论文
TUMOR BIOLOGY, 2015, 卷号: 36, 期号: 12, 页码: 9667-9676
作者:  Wu, Ning;  Liu, Jia;  Zhao, Xiangzhong;  Yan, Zhiyong;  Jiang, Bo;  Wang, Lijun;  Cao, Shousong;  Shi, Dayong;  Lin, Xiukun
Adobe PDF(1959Kb)  |  收藏  |  浏览/下载：251/1  |  提交时间：2016/02/05
Cardamonin  Glioblastoma Stem Cell  Stat3  Apoptosis  Temozolomide  Self-renewal  
Cloning and characterization of a novel caspase-8-like gene in Crassostrea gigas 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 46, 期号: 2, 页码: 486-492
作者:  Li, Chunyan;  Qu, Tao;  Huang, Baoyu;  Ji, Peng;  Huang, Wen;  Que, Huayong;  Li, Li;  Zhang, Guofan
Adobe PDF(848Kb)  |  收藏  |  浏览/下载：265/1  |  提交时间：2015/12/15
Crassostrea Gigas  Cgcaspase8-2  Apoptosis  Immune Response  
Characterization of an inhibitor of apoptosis protein in Crassostrea gigas clarifies its role in apoptosis and immune defense 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 51, 期号: 1, 页码: 74-78
作者:  Qu, Tao;  Zhang, Linlin;  Wang, Wei;  Huang, Baoyu;  Li, Yingxiang;  Zhu, Qihui;  Li, Li;  Zhang, Guofan
Adobe PDF(823Kb)  |  收藏  |  浏览/下载：250/1  |  提交时间：2015/12/07
Crassostrea Gigas  Iap  Evolution  Intrinsic Apoptosis  Caspase  Immune Response  
Identification and functional characterization of two Bc1-2 family protein genes in Zhikong scallop Chlamys farreri 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 44, 期号: 1, 页码: 147-155
作者:  Qi, Haigang;  Miao, Guoying;  Li, Li;  Que, Huayong;  Zhang, Guofan
Adobe PDF(3305Kb)  |  收藏  |  浏览/下载：237/1  |  提交时间：2015/07/07
Apoptosis  Zhikong Scallop  Chlamys Farreri  Cfbcl-2  Cfbax  
Transcriptome Analysis Reveals a Rich Gene Set Related to Innate Immunity in the Eastern Oyster (Crassostrea virginica) 期刊论文
MARINE BIOTECHNOLOGY, 2014, 卷号: 16, 期号: 1, 页码: 17-33
作者:  Zhang, Linlin;  Li, Li;  Zhu, Yabing;  Zhang, Guofan;  Guo, Ximing;  Zhang, GF (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(1259Kb)  |  收藏  |  浏览/下载：250/0  |  提交时间：2015/06/11
Innate Immunity  Apoptosis  Transcriptome  Disease  Adaptation  Mollusca  
p38 MAPK Signaling Mediates Mitochondrial Apoptosis in Cancer Cells Induced by Oleanolic Acid 期刊论文
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 卷号: 15, 期号: 11, 页码: 4519-4525
作者:  Liu, Jia;  Wu, Ning;  Ma, Lei-Na;  Zhong, Jia-Teng;  Liu, Ge;  Zheng, Lan-Hong;  Lin, Xiu-Kun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao, Peoples R China.
Adobe PDF(1193Kb)  |  收藏  |  浏览/下载：227/0  |  提交时间：2015/06/11
Oleanolic Acid  Apoptosis  P38 Mapk  Cancer  Ros  
Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells 期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2013, 卷号: 33, 期号: 8, 页码: 756-765
作者:  Wei, Jianteng;  Liu, Ming;  Liu, Haizhou;  Wang, Hui;  Wang, Fengxia;  Zhang, Yuyan;  Han, Lijun;  Lin, Xiukun;  Lin, XK
Adobe PDF(2882Kb)  |  收藏  |  浏览/下载：279/0  |  提交时间：2014/07/17
Oleanolic Acid  Apoptosis  Ros  Mitochondrial Depolarization  Lysosomal Membrane Permeabilization  
The oyster genome reveals stress adaptation and complexity of shell formation 期刊论文
NATURE, 2012, 卷号: 490, 期号: 7418, 页码: 49-54
作者:  Zhang, Guofan;  Fang, Xiaodong;  Guo, Ximing;  Li, Li;  Luo, Ruibang;  Xu, Fei;  Yang, Pengcheng;  Zhang, Linlin;  Wang, Xiaotong;  Qi, Haigang;  Xiong, Zhiqiang;  Que, Huayong;  Xie, Yinlong;  Holland, Peter W. H.;  Paps, Jordi;  Zhu, Yabing;  Wu, Fucun;  Chen, Yuanxin;  Wang, Jiafeng;  Peng, Chunfang;  Meng, Jie;  Yang, Lan;  Liu, Jun;  Wen, Bo;  Zhang, Na;  Huang, Zhiyong;  Zhu, Qihui;  Feng, Yue;  Mount, Andrew;  Hedgecock, Dennis;  Xu, Zhe;  Liu, Yunjie;  Domazet-Loso, Tomislav;  Du, Yishuai;  Sun, Xiaoqing;  Zhang, Shoudu;  Liu, Binghang;  Cheng, Peizhou;  Jiang, Xuanting;  Li, Juan;  Fan, Dingding;  Wang, Wei;  Fu, Wenjing;  Wang, Tong;  Wang, Bo;  Zhang, Jibiao;  Peng, Zhiyu;  Li, Yingxiang;  Li, Na;  Wang, Jinpeng;  Chen, Maoshan;  He, Yan;  Tan, Fengji;  Song, Xiaorui;  Zheng, Qiumei;  Huang, Ronglian;  Yang, Hailong;  Du, Xuedi;  Chen, Li;  Yang, Mei;  Gaffney, Patrick M.;  Wang, Shan;  Luo, Longhai;  She, Zhicai;  Ming, Yao;  Huang, Wen;  Zhang, Shu;  Huang, Baoyu;  Zhang, Yong;  Qu, Tao;  Ni, Peixiang;  Miao, Guoying;  Wang, Junyi;  Wang, Qiang;  Steinberg, Christian E. W.;  Wang, Haiyan;  Li, Ning;  Qian, Lumin;  Zhang, Guojie;  Li, Yingrui;  Yang, Huanming;  Liu, Xiao;  Wang, Jian;  Yin, Ye;  Wang, Jun;  Wang, J (reprint author), BGI Shenzhen, Shenzhen 518083, Peoples R China.
Adobe PDF(712Kb)  |  收藏  |  浏览/下载：1351/2  |  提交时间：2013/09/24
Transposable Elements  Crassostrea-gigas  Bivalve Mollusks  Parahox Genes  Proteins  Sequence  Evolution  Discovery  Apoptosis  Pathway