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Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载：287/0  |  提交时间：2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：345/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：261/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
作者:  Zhang, Renshuai;  Song, Lairong;  Jiang, Bo;  Wang, Lijun;  Wu, Ning;  Guo, Shuju;  Shi, Dayong
Adobe PDF(1892Kb)  |  收藏  |  浏览/下载：223/0  |  提交时间：2017/09/30
Saccharide  Glut1  Drug Design  Anticancer  Cell Uptake  
Metamorphic P-T-t paths of pelitic granulites of the Taihua metamorphic complex in the Mts. Huashan area and tectonothermal implications for the Palaeoproterozoic Trans-North China Orogen 期刊论文
PRECAMBRIAN RESEARCH, 2017, 卷号: 290, 页码: 147-162
作者:  Wang, Guo-Dong;  Wang, Hao Y. C.;  Chen, Hong-Xu;  Lu, Jun-Sheng;  Zhang, Bo;  Van Tho Pham;  Zhang, Ji-Jun;  Zhang, Qing;  Wu, Chun-Ming
Adobe PDF(4723Kb)  |  收藏  |  浏览/下载：232/0  |  提交时间：2017/07/05
Pelitic Granulites  Taihua Metamorphic Complex  Metamorphic P-t-t Path  North China Craton  
Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 8, 页码: 683-692
作者:  Wang, Bao-Cheng;  Wang, Li-Jun;  Jiang, Bo;  Wang, Shuai-Yu;  Wu, Ning;  Li, Xiang-Qian;  Shi, Da-Yong
Adobe PDF(1080Kb)  |  收藏  |  浏览/下载：273/0  |  提交时间：2017/09/30
Application Of Fluorine  Anticancer  Antimicrobial  Anti-inflammatory  Antivirus Activity  Drug Design  Importance Of Fluorinated Compounds  
Geochronology and geochemistry of the TTG and potassic granite of the Taihua complex, Mts. Huashan: Implications for crustal evolution of the southern North China Craton 期刊论文
PRECAMBRIAN RESEARCH, 2017, 卷号: 288, 页码: 72-90
作者:  Wang, Guo-Dong;  Wang, Hao Y. C.;  Chen, Hong-Xu;  Zhang, Bo;  Zhang, Qing;  Wu, Chun-Ming
Adobe PDF(7069Kb)  |  收藏  |  浏览/下载：238/0  |  提交时间：2017/03/22
Ttg  Potassic Granite  Geochronology  Geochemistry  Taihua Complex  North China Craton