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Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：163/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
The Effect of Pedal Peptide-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus 期刊论文
FRONTIERS IN PHYSIOLOGY, 2020, 卷号: 11, 页码: 11
作者:  Ding, Kui;  Zhang, Libin;  Fan, Xinhao;  Guo, Xueying;  Liu, Xiang;  Yang, Hongsheng
Adobe PDF(2909Kb)  |  收藏  |  浏览/下载：244/0  |  提交时间：2021/04/12
echinoderm  locomotor performance  muscle metabolite  pedal peptide  neuropeptide  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：303/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder-Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 20, 页码: 18
作者:  Li, Wenrui;  Guan, Xiaolu;  Sun, Li
Adobe PDF(3489Kb)  |  收藏  |  浏览/下载：160/0  |  提交时间：2021/04/12
Paralichthys olivaceus  microRNA  phosphatase and tensin homolog  pathogen infection  immune defense  autophagy  apoptosis  
Molecular cloning, characterization and expression profiles of CD2AP in Nile tilapia (Oreochromis niloticus) responding to Streptococcus agalactiae infection and interaction with CD2 cytoplasmic segment 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 101, 页码: 205-215
作者:  Li, Yuan;  Wang, Bei;  Wang, Zhi-wen;  Huang, Yu;  Jian, Ji-chang;  Lu, Yi-shan
Adobe PDF(4191Kb)  |  收藏  |  浏览/下载：171/0  |  提交时间：2020/09/24
CD2-associated protein  Nile tilapia  CD2  Immune response  T cells activation  Streptococcus agalactiae  
四株深海真菌次级代谢产物化学多样性及生物活性研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
作者:  迟路坪
Adobe PDF(8344Kb)  |  收藏  |  浏览/下载：257/0  |  提交时间：2020/06/10
深海真菌  海洋天然产物  次级代谢产物  生物活性  
热激转录因子1和热激蛋白在牡蛎热响应中的作用机制研究 学位论文
农学博士, 中国科学院海洋研究所: 中国科学院大学, 2020
作者:  刘优利
Adobe PDF(22222Kb)  |  收藏  |  浏览/下载：353/1  |  提交时间：2020/06/10
牡蛎  热激  热激转录因子1  热激蛋白  调控关系  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：197/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
Adobe PDF(2455Kb)  |  收藏  |  浏览/下载：263/0  |  提交时间：2020/09/25
CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Comparative transcriptomic analysis of deep- and shallow-water barnacle species (Cirripedia, Poecilasmatidae) provides insights into deep-sea adaptation of sessile crustaceans 期刊论文
BMC GENOMICS, 2020, 卷号: 21, 期号: 1, 页码: 13
作者:  Gan, Zhibin;  Yuan, Jianbo;  Liu, Xinming;  Dong, Dong;  Li, Fuhua;  Li, Xinzheng
Adobe PDF(2419Kb)  |  收藏  |  浏览/下载：145/0  |  提交时间：2020/09/23
Barnacle  Deep-sea habitat  Transcriptome  Adaptation