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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载:4/0  |  提交时间:2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Comparative chromatin dynamics reveal differential thermal tolerance mechanisms between two congeneric oyster species 期刊论文
AQUACULTURE, 2024, 卷号: 579, 页码: 16
作者:  Wang, Chaogang;  Jiang, Zhuxiang;  Du, Mingyang;  Li, Qingyuan;  Cong, Rihao;  Wang, Wei;  Zhang, Guofan;  Li, Li
收藏  |  浏览/下载:1/0  |  提交时间:2024/04/07
Crassostrea gigas  Crassostrea angulata  ATAC-seq  RNA-Seq  Thermal tolerance  
Autophagy contributes to increase the content of intracellular free amino acids in hard clam (Mercenaria mercenaria) during prolonged exposure to hypersaline environments 期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:  Zhou, Cong;  Yang, Mei-jie;  Hu, Zhi;  Zou, Yan;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Song, Hao;  Zhang, Tao
Adobe PDF(5375Kb)  |  收藏  |  浏览/下载:158/1  |  提交时间:2023/11/30
Hyposalinity  Hypersalinity  Transcriptome  Autophagy  Free amino acids  
Synergistic modulation of neuroendocrine-inflammation pathway by microRNAs facilitates intertidal adaptation of molluscs 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 142, 页码: 10
作者:  Chen, Hao;  Wang, Lin;  Wang, Lingling;  Zhang, Huan;  Wang, Hao;  Song, Linsheng
Adobe PDF(6028Kb)  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/04/07
Inflammation response  Calmodulin  Nitrite oxide  Tumor necrosis factor  miRNAs  Aerial exposure  
Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 266, 页码: 11
作者:  Ding, Kui;  Xu, Qinzeng;  Zhang, Xuelei;  Liu, Shilin
Adobe PDF(3947Kb)  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/04/07
Apostichopus japonicus  BDE-47  Nervous system  UPLC-Triple-TOF-MS  Metabolite  Neurotoxicity  
Population genetic structure and implication for adaptive differentiation of the snail (Gastropoda, Provannidae) in deep-sea chemosynthetic ecosystems 期刊论文
ZOOLOGICA SCRIPTA, 2023, 页码: 15
作者:  Zhang, Yu;  Cheng, Jiao;  Sha, Zhongli;  Hui, Min
Adobe PDF(5970Kb)  |  收藏  |  浏览/下载:109/0  |  提交时间:2023/11/30
adaptive evolution  chemosynthetic ecosystem  gastropod  population genetics  RAD-seq  
ROS-induced moderate autophagy of haemocytes confers resistance of Mercenaria mercenaria to air exposure stress 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
作者:  Zhou, Cong;  Zou, Yan;  Hu, Zhi;  Yang, Mei-jie;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Zhang, Tao;  Song, Hao
Adobe PDF(8330Kb)  |  收藏  |  浏览/下载:5/1  |  提交时间:2024/04/07
Air exposure  Resistance  Haemocytes  Oxidative stress  Autophagy  
Integrated analysis of a miRNA-mRNA network related to immunity and autophagy in Macrobrachium rosenbergii infected with Aeromonas hydrophila 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
作者:  Wang, Feifei;  Zhao, Fei;  Tan, Aiping;  Deng, Yuting;  Wang, Ling;  Gong, Hua;  Lai, Yingliao;  Huang, Zhibin;  Li, Fuhua
Adobe PDF(6146Kb)  |  收藏  |  浏览/下载:84/0  |  提交时间:2023/11/30
Macrobrachium rosenbergii  miRNA-mRNA  Immunity  Autophagy  Aeromonas hydrophila  
Characterization of the pathogenicity of a Bacillus cereus isolate from the Mariana Trench 期刊论文
VIRULENCE, 2022, 卷号: 13, 期号: 1, 页码: 1062-1075
作者:  Wang, Yujian;  Zhang, Jian;  Yuan, Zihao;  Sun, Li
Adobe PDF(22363Kb)  |  收藏  |  浏览/下载:214/0  |  提交时间:2022/07/18
Bacillus cereus  deep sea  pathogenicity  cytotoxicity  spore  
Cryptochrome 1 is involved in anti-bacterial immunity in Japanese flounder (Paralichthys olivaceus) 期刊论文
AQUACULTURE, 2022, 卷号: 561, 页码: 11
作者:  Zhang, Peng;  Sun, Boguang
Adobe PDF(11965Kb)  |  收藏  |  浏览/下载:131/0  |  提交时间:2023/01/04
Paralichthys olivaceus  Circadian protein  Cryptochrome 1  Immune response  Bacterial infection