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An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载：168/0  |  提交时间：2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
Structural and Bioactive Studies of Halogenated Constituents from Sponges 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 14, 页码: 2335-2360
作者:  Li, Chao;  Shi, Dayong
收藏  |  浏览/下载：210/0  |  提交时间：2020/09/24
Halogenated  sponges  marine  isolate  constitutes  activity  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2683Kb)  |  收藏  |  浏览/下载：252/0  |  提交时间：2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
Halogenated Compounds from Corals: Chemical Diversity and Biological Activities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 15, 页码: 1204-1218
作者:  Zhang, Yuanyuan;  Liu, Junhong;  Shi, Dayong;  Li, Zheng
收藏  |  浏览/下载：129/0  |  提交时间：2020/09/21
Marine  corals  metabolites  halogenated  bioactivity  chemical diversity  
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
作者:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling;  Li, Xiangqian;  Wang, Lijun;  Guo, Chuanlong;  Wu, Ning;  Shi, Dayong
Adobe PDF(2211Kb)  |  收藏  |  浏览/下载：265/0  |  提交时间：2019/08/20
Recent Advances in Transition-metal-catalyzed Halides Formation 期刊论文
CURRENT ORGANIC CHEMISTRY, 2018, 卷号: 22, 期号: 23, 页码: 2229-2255
作者:  Shi, Xiaolin;  Shi, Dayong
Adobe PDF(1243Kb)  |  收藏  |  浏览/下载：215/0  |  提交时间：2019/05/15
Catalysis  C-X bond  halides formation  halogenated  organohalides  palladium  transition metals