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A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：350/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：265/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability  
A review of the components of brown seaweeds as potential candidates in cancer therapy 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 15, 页码: 12592-12610
作者:  Hussain, Ejaz;  Wang, Li-Jun;  Jiang, Bo;  Riaz, Saba;  Butt, Ghazala Yasmeen;  Shi, Da-Yong
Adobe PDF(1506Kb)  |  收藏  |  浏览/下载：293/2  |  提交时间：2016/05/03
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 7, 页码: 4452-4469
作者:  Luo, Jiao;  Wu, Ning;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Wang, Baocheng;  Wang, Changhui;  Shi, Dayong
Adobe PDF(1638Kb)  |  收藏  |  浏览/下载：256/2  |  提交时间：2015/12/07
Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 806-823
作者:  Wang, Li-Jun;  Wang, Shuai-Yu;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Wang, Bao-Cheng;  Luo, Jiao;  Yang, Meng;  Jin, Shui-Hua;  Shi, Da-Yong
Adobe PDF(1301Kb)  |  收藏  |  浏览/下载：244/0  |  提交时间：2015/06/15
Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 60, 页码: 48822-48834
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(1045Kb)  |  收藏  |  浏览/下载：226/1  |  提交时间：2015/07/27
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载：264/0  |  提交时间：2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao;  Shi, DY
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：321/1  |  提交时间：2014/07/17
Type 2 Diabetes Mellitus  Protein Tyrosine Phosphatase 1b  Bromophenol  Anti-diabetic Activities  
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:  Shi, Dayong;  Guo, Shuju;  Jiang, Bo;  Guo, Chao;  Wang, Tao;  Zhang, Luyong;  Li, Jingya;  Shi, DY
Adobe PDF(662Kb)  |  收藏  |  浏览/下载：269/0  |  提交时间：2014/07/17
Bromophenol  Protein Tyrosine Phosphatase 1b Inhibitor  Db/db Mouse Model  Anti-diabetes Properties  
Synthesis and protein tyrosine phosphatase 1B inhibition activities of two new synthetic bromophenols and their methoxy derivatives 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 6, 页码: 1237-1242
作者:  Cui Yongchao;  Shi Dayong;  Hu Zhiqiang
Adobe PDF(413Kb)  |  收藏  |  浏览/下载：254/1  |  提交时间：2012/07/03
Protein Tyrosine Phosphatase 1b Inhibition  Bromophenol Derivatives  Synthesis