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A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Jiang, Bo;  Wu, Ning;  Guo, Shuju;  Zhang, Renshuai;  Liu, Kun;  Shi, Dayong
Adobe PDF(1849Kb)  |  收藏  |  浏览/下载：359/0  |  提交时间：2018/01/11
Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载：319/0  |  提交时间：2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33
作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Guo, Shuju;  Wu, Ning;  Shi, Dayong
Adobe PDF(3126Kb)  |  收藏  |  浏览/下载：273/0  |  提交时间：2017/07/10
Ptp1b  Bromophenol  Saccharide  Selectivity  Permeability