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Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:341/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  收藏  |  浏览/下载:228/0  |  提交时间:2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
Amh dominant expression in Sertoli cells during the testicular differentiation and development stages in the olive flounder Paralichthys olivaceus 期刊论文
GENE, 2020, 卷号: 755, 页码: 9
作者:  Wang, Wenxiang;  Liang, Shaoshuai;  Zou, Yuxia;  Wu, Zhihao;  Wang, Lijuan;  Liu, Yan;  You, Feng
Adobe PDF(2594Kb)  |  收藏  |  浏览/下载:275/0  |  提交时间:2020/09/25
Olive flounder Paralichthys olivaceus  Amh  Expression  Testicular differentiation and development  Somatic cell  
Bisphenol A-associated alterations in DNA and histone methylation affects semen quality in rare minnow Gobiocypris rarus 期刊论文
AQUATIC TOXICOLOGY, 2020, 卷号: 226, 页码: 11
作者:  Zhu, Long;  Yuan, Cong;  Wang, Mingrong;  Liu, Yan;  Wang, Zaizhao;  Seif, Mohamed M.
Adobe PDF(3794Kb)  |  收藏  |  浏览/下载:185/0  |  提交时间:2020/10/26
Bisphenol A  DNA methylation  Histone methylation  Gobiocypris rarus  
Effects of different flow velocities on behavior and TRPA1 expression in the sea cucumberApostichopus japonicas 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 4, 页码: 1328-1340
作者:  Lin Chenggang;  Liu Xiaolu;  Sun Lina;  Liu Shilin;  Sun Jingchun;  Zhang Libin;  Yang Hongsheng
Adobe PDF(2851Kb)  |  收藏  |  浏览/下载:214/0  |  提交时间:2020/09/25
sea cucumber  Apostichopus japonicus  behavior  flow velocity  transient receptor potential cation channel subfamily A  member 1 (TRPA1)  
An insulin-like peptide serves as a regulator of glucose metabolism in the immune response of Chinese mitten crab Eriocheir sinensis 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 卷号: 108, 页码: 9
作者:  Wang, Lin;  Chen, Hao;  Wang, Lingling;  Song, Linsheng
Adobe PDF(7707Kb)  |  收藏  |  浏览/下载:281/0  |  提交时间:2020/09/23
Aeromonas hydrophila infection  Chinese mitten crab  Glucose metabolism  Insulin-like peptide  Immune response  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载:227/0  |  提交时间:2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
Behavioural response of different epithelial tissues of sea cucumber (Apostichopus japonicus) to light and differential expression of the light-related genePax6 期刊论文
MARINE AND FRESHWATER BEHAVIOUR AND PHYSIOLOGY, 2020, 卷号: 53, 期号: 2, 页码: 73-85
作者:  Liu, Xiaolu;  Chenggang, Lin;  Sun, Lina;  Liu, Shilin;  Sun, Jingchun;  Yang, Hongsheng
Adobe PDF(1947Kb)  |  收藏  |  浏览/下载:210/0  |  提交时间:2021/04/12
Apostichopus japonicus  behaviour  Pax6  epithelial tissue  illumination  
Effects of environmental stress (sex steroids and heat) during sex differentiation in Japanese flounder (Paralichthys olivaceus): insight from germ cell proliferation and gsdf-amh-cyp19a1a expression 期刊论文
AQUACULTURE, 2020, 卷号: 515, 页码: 8
作者:  Yang, Yang;  Liu, Qinghua;  Xiao, Yongshuang;  Xu, Shihong;  Wang, Xueying;  Yang, Jingkun;  Song, Zongcheng;  You, Feng;  Li, Jun
Adobe PDF(4237Kb)  |  收藏  |  浏览/下载:208/0  |  提交时间:2020/09/21
Gonadal development  Japanese flounder  High temperature  Sex steroids  gsdf/amh/cyp19a1a