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The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载:289/0  |  提交时间:2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
Sea cucumbers in a high temperature and low dissolved oxygen world: Roles of miRNAs in the regulation of environmental stresses 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 268, 页码: 9
作者:  Huo, Da;  Sun, Lina;  Sun, Jingchun;  Zhang, Libin;  Liu, Shilin;  Su, Fang;  Yang, Hongsheng
Adobe PDF(3090Kb)  |  收藏  |  浏览/下载:226/0  |  提交时间:2021/04/21
Global climate change  MicroRNA  Apostichopus japonicus  Anoxia  Heat  
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun;  Fan, Junting;  Di, Guohu;  Guo, Chuanlong
Adobe PDF(8144Kb)  |  收藏  |  浏览/下载:175/0  |  提交时间:2021/04/21
PARP inhibitor  BRCA  Pancreatic cancer  
Progress in Research on Bioactive Secondary Metabolites from Deep-Sea Derived Microorganisms 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 12, 页码: 26
作者:  Wang, Ya-Nan;  Meng, Ling-Hong;  Wang, Bin-Gui
Adobe PDF(5301Kb)  |  收藏  |  浏览/下载:217/0  |  提交时间:2021/04/12
deep-sea fungi  deep-sea actinomycetes  secondary metabolites  bioactivity  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载:197/0  |  提交时间:2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
Marine bacterial surfactin CS30-2 induced necrosis-like cell death in Huh7.5 liver cancer cells 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 3, 页码: 826-833
作者:  Zhou Shengnan;  Liu Ge;  Wu Shimei
Adobe PDF(2021Kb)  |  收藏  |  浏览/下载:186/0  |  提交时间:2020/09/24
Bacillus  surfactin  anticancer activity  reactive oxygen species (ROS)  
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
作者:  Guo, Chuanlong;  Hou, Yuzhen;  Yu, Xuemin;  Zhang, Fan;  Wu, Xiaochen;  Wu, Xianggen;  Wang, Lijun
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载:181/0  |  提交时间:2020/09/22
Apoptosis  eIF4F  ERK  MNK  A549 cells  
Effects of ammonia stress on the hemocytes of the Pacific white shrimp Litopenaeus vannamei 期刊论文
CHEMOSPHERE, 2020, 卷号: 239, 页码: 12
作者:  Liu, Fei;  Li, Shihao;  Yu, Yang;  Sun, Mingzhe;  Xiang, Jianhai;  Li, Fuhua
Adobe PDF(1954Kb)  |  收藏  |  浏览/下载:287/0  |  提交时间:2020/03/20
Ammonia stress  Metabolome  Transcriptome  Hemocytes  Litopenaeus vannamei  
H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:  Li, Fengli;  Wang, Jing;  Wu, Ning;  Zhang, Hua;  Li, Zheng;  Wei, Ning
Adobe PDF(1665Kb)  |  收藏  |  浏览/下载:208/0  |  提交时间:2020/03/20
5-FU  Drug resistance  STAT3  Hepatocellular carcinoma  MCL-1  PUMA  
Hemolymph C1qDC promotes the phagocytosis of oyster Crassostrea gigas hemocytes by interacting with the membrane receptor beta-integrin 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 98, 页码: 42-53
作者:  Lv, Zhao;  Wang, Lingling;  Jia, Zhihao;  Sun, Jiejie;  Wang, Weilin;  Liu, Zhaoqun;  Qiu, Limei;  Wang, Mengqiang;  Song, Linsheng
Adobe PDF(1932Kb)  |  收藏  |  浏览/下载:291/0  |  提交时间:2019/08/29
Phagocytosis  C1qDC  Opsonization  beta-Integrin  Oyster Crassostrea gigas