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Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides 期刊论文
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2021, 卷号: 56, 页码: 5
作者:  Li, Ke;  Li, Xiao-Ming;  Gloer, James B.;  Wang, Bin-Gui
Adobe PDF(541Kb)  |  收藏  |  浏览/下载：137/0  |  提交时间：2021/12/07
Marine red alga  Rhodomela confervoides  Ureidobromophenols  Antioxidant activity  
海洋溴酚化合物对肠道菌群的调节与益生菌降糖作用研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2021
作者:  张良
Adobe PDF(5745Kb)  |  收藏  |  浏览/下载：186/0  |  提交时间：2021/06/17
海洋溴酚化合物，肠道微生物，菌群结构，益生特性，降糖作用  
Chlororespiration protects the photosynthetic apparatus against photoinhibition by alleviating inhibition of photodamaged-PSII repair in Haematococcus pluvialis at the green motile stage 期刊论文
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2021, 卷号: 54, 页码: 8
作者:  Zhao, Jing;  Yu, Wenjie;  Zhang, Litao;  Liu, Jianguo
Adobe PDF(1722Kb)  |  收藏  |  浏览/下载：213/0  |  提交时间：2021/05/11
Chlororespiration  Plastid terminal oxidase  Photoprotection  Haematococcus pluvialis  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：191/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun;  Fan, Junting;  Di, Guohu;  Guo, Chuanlong
Adobe PDF(8144Kb)  |  收藏  |  浏览/下载：175/0  |  提交时间：2021/04/21
PARP inhibitor  BRCA  Pancreatic cancer  
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:  Luo, Jiao;  Zhang, Renshuai;  Wang, Xuehe;  Hou, Zhanhui;  Guo, Shuju;  Jiang, Bo
Adobe PDF(3013Kb)  |  收藏  |  浏览/下载：163/0  |  提交时间：2021/04/12
PTP1B  Bromophenol  Molecular docking  Surface plasmon resonance  
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：302/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 160, 页码: 496-505
作者:  Wang, Jun;  Wang, Lijun;  Zhang, Shuhong;  Fan, Junting;  Yang, Hui;  Li, Qiqi;  Guo, Chuanlong
Adobe PDF(3920Kb)  |  收藏  |  浏览/下载：202/0  |  提交时间：2020/10/26
eIF4E/eIF4G  Human lung cancer  Apoptosis  DNA damage  ROS  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
Adobe PDF(2455Kb)  |  收藏  |  浏览/下载：263/0  |  提交时间：2020/09/25
CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats 期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 6, 页码: 3429-3437
作者:  Guo, Shuju;  Wang, Lijun;  Chen, Dong;  Jiang, Bo
Adobe PDF(699Kb)  |  收藏  |  浏览/下载：269/0  |  提交时间：2020/03/20