中文版 | English

在结果中检索

IOCAS-IR

浏览/检索结果: 共8条，第1-8条 帮助

限定条件                    
已选(0)清除 条数/页：   排序方式：
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载：327/0  |  提交时间：2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载：334/0  |  提交时间：2020/03/20
Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 10
作者:  Shi, Xiaolin;  Li, Xiaowei;  Li, Xiangqian;  Shi, Dayong
Adobe PDF(988Kb)  |  收藏  |  浏览/下载：298/0  |  提交时间：2020/01/03
C-H functionalization  trifluoromethylation  indoles  copper  radical reaction  
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2683Kb)  |  收藏  |  浏览/下载：271/0  |  提交时间：2019/08/28
bromophenol  apoptosis  autophagy  phosphoinositide 3-kinase  protein kinase B  mechanistic target of rapamycin signaling  reactive oxygen species  
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue;  Wang, Lijun;  Jiang, Bo;  Shi, Dayong
Adobe PDF(2321Kb)  |  收藏  |  浏览/下载：211/0  |  提交时间：2019/05/15
Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity  
Cu(II)-Catalyzed Oxidative Trifluoromethylation of Indoles with KF as the Base 期刊论文
CATALYSTS, 2019, 卷号: 9, 期号: 3, 页码: 14
作者:  Shi, Xiaolin;  Li, Xiaowei;  Ma, Lina;  Shi, Dayong
Adobe PDF(1208Kb)  |  收藏  |  浏览/下载：340/0  |  提交时间：2019/08/28
Cu(II) catalyst  Langlois reagent  trifluoromethylation  indole  radical reaction  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：305/0  |  提交时间：2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
Recent Advances in Transition-metal-catalyzed Halides Formation 期刊论文
CURRENT ORGANIC CHEMISTRY, 2018, 卷号: 22, 期号: 23, 页码: 2229-2255
作者:  Shi, Xiaolin;  Shi, Dayong
Adobe PDF(1243Kb)  |  收藏  |  浏览/下载：225/0  |  提交时间：2019/05/15
Catalysis  C-X bond  halides formation  halogenated  organohalides  palladium  transition metals