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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载:202/0  |  提交时间:2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Transcriptome analysis reveals the effects of sand substrate removal and body colour change of kuruma shrimp,Marsupenaeus japonicus 期刊论文
AQUACULTURE RESEARCH, 2020, 页码: 12
作者:  Zhao, Jichen;  Liu, Xueting;  Liao, Xuzheng;  He, Zihao;  Chen, Xieyan;  Sun, Chengbo;  Ni, Zuotao
Adobe PDF(1009Kb)  |  收藏  |  浏览/下载:270/0  |  提交时间:2021/04/12
body colour  Marsupenaeus japonicus  physiological activities  substrates  transcriptome  
Integrated proteomics and metabolomics analysis reveals the antifungal mechanism of the C-coordinated O-carboxymethyl chitosan Cu (II) complex 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 155, 页码: 1491-1509
作者:  Ma, Yuzhen;  Yu, Huahua;  Liu, Weixiang;  Qin, Yukun;  Xing, Ronge;  Li, Pengcheng
Adobe PDF(13837Kb)  |  收藏  |  浏览/下载:247/0  |  提交时间:2020/09/24
Natural organic-based copper  O-CSLn-Cu  Phytophthora capsici Leonian  Proteomics-metabonomics integrated analysis  Antifungal mechanism  
Enterococcus faecalis alpha 1-2-mannosidase (EfMan-I): an efficient catalyst for glycoprotein N-glycan modification 期刊论文
FEBS LETTERS, 2020, 卷号: 594, 期号: 3, 页码: 439-451
作者:  Li, Yanhong;  Li, Riyao;  Yu, Hai;  Sheng, Xue;  Wang, Jing;  Fisher, Andrew J.;  Chen, Xi
Adobe PDF(1273Kb)  |  收藏  |  浏览/下载:302/0  |  提交时间:2020/01/03
alpha-mannosidase  crystal structure  glycoprotein modification  mannosidase  N-glycan enzymatic modification  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载:306/0  |  提交时间:2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade 期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 1, 页码: 55-69
作者:  Xu, Qi;  Wang, Lijun;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2267Kb)  |  收藏  |  浏览/下载:217/0  |  提交时间:2018/04/02
Type 2 Diabetes Mellitus  Insulin Resistance  Insulin Secretion  Targets  Mechanism  Drugs  
The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 7, 页码: 861-878
作者:  Jin, Qiu;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(757Kb)  |  收藏  |  浏览/下载:290/0  |  提交时间:2019/08/21
Anti-obesity  marine-derived  digestive enzyme  appetite  fat absorption  adipogenesis  thermogenesis  utilization  
iTRAQ reveals proteomic changes during intestine regeneration in the sea cucumber Apostichopus japonicus 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2017, 卷号: 22, 页码: 39-49
作者:  Sun, Lina;  Xu, Dongxue;  Xu, Qinzeng;  Sun, Jingchun;  Xing, Lili;  Zhang, Libin;  Yang, Hongsheng
Adobe PDF(838Kb)  |  收藏  |  浏览/下载:400/1  |  提交时间:2017/07/10
Sea Cucumber  Intestine Regeneration  Itraq  Proteomics  
Understanding mechanism of sea cucumber Apostichopus japonicus aestivation: Insights from TMT-based proteomic study 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2016, 卷号: 19, 页码: 78-89
作者:  Chen, Muyan;  Li, Xingke;  Zhu, Aijun;  Storey, Kenneth B.;  Sun, Lina;  Gao, Tianxiang;  Wang, Tianming
Adobe PDF(1152Kb)  |  收藏  |  浏览/下载:280/0  |  提交时间:2016/11/02
Aestivation  Sea Cucumber  Proteome  Tandem Mass Tag  Post-transcriptional Regulation  
A review of the components of brown seaweeds as potential candidates in cancer therapy 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 15, 页码: 12592-12610
作者:  Hussain, Ejaz;  Wang, Li-Jun;  Jiang, Bo;  Riaz, Saba;  Butt, Ghazala Yasmeen;  Shi, Da-Yong
Adobe PDF(1506Kb)  |  收藏  |  浏览/下载:298/2  |  提交时间:2016/05/03