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Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT07 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 365, 页码: 8
作者:  Yue, Yang;  Yu, Huahua;  Suo, Qishan;  Li, Rongfeng;  Liu, Song;  Xing, Ronge;  Zhang, Quanbin;  Li, Pengcheng
Adobe PDF(4816Kb)  |  收藏  |  浏览/下载：162/0  |  提交时间：2023/01/04
Nemopilema nomurai  Jellyfish envenomations  Aspergillus versicolor  Metalloproteinase inhibitors  Molecular docking  
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：191/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
Characteristics and sex dimorphism of 17 beta-hydroxysteroid dehydrogenase family genes in the olive flounder Paralichthys olivaceus 期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2020, 卷号: 199, 页码: 17
作者:  Zou, Congcong;  Wang, Lijuan;  Zou, Yuxia;  Wu, Zhihao;  Wang, Wenxiang;  Liang, Shaoshuai;  Wang, Ling;  You, Feng
Adobe PDF(13269Kb)  |  收藏  |  浏览/下载：198/0  |  提交时间：2020/09/23
Olive flounder Paralichthys olivaceus  Hsd17b  Gene characteristics  Expression  Sex hormone receptor inhibitors  Gonadal development  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：289/0  |  提交时间：2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
Functional Elucidation of Nemopilema nomurai and Cyanea nozakii Nematocyst Venoms' Lytic Activity Using Mass Spectrometry and Zymography 期刊论文
TOXINS, 2017, 卷号: 9, 期号: 2
作者:  Yue, Yang;  Yu, Huahua;  Li, Rongfeng;  Xing, Ronge;  Liu, Song;  Li, Kecheng;  Wang, Xueqin;  Chen, Xiaolin;  Li, Pengcheng
Adobe PDF(5507Kb)  |  收藏  |  浏览/下载：253/0  |  提交时间：2017/07/05
Zymography  Lc-ms/ms  Enzymatic Toxins  Hemolysis  Jellyfish Metalloproteinase Inhibitors  Pla(2) Inhibitors  Nemopilema Nomurai  Cyanea Nozakii  
Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 46, 页码: 14248-14254
作者:  Song, Ting;  Wang, Ziqian;  Ji, Fangling;  Feng, Yingang;  Fan, Yudan;  Chai, Gaobo;  Li, Xiangqian;  Li, Zhiqiang;  Zhang, Zhichao
Adobe PDF(5903Kb)  |  收藏  |  浏览/下载：216/0  |  提交时间：2016/12/12
Apoptosis  Conformation Analysis  Drug Design  Inhibitors  Structure Elucidation  
cDNA cloning, characterization and mRNA expression of a pacifastin light chain gene from the Chinese mitten crab Eriocheir sinensis 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2008, 卷号: 25, 期号: 5, 页码: 657-663
作者:  Gai, Yunchao;  Wang, Lingling;  Song, Linsheng;  Zhao, Jianmin;  Qiu, Limei;  Wang, Bo;  Mu, Changkao;  Zheng, Peilin;  Zhang, Ying;  Li, Ling;  Xing, Kezhi
Adobe PDF(726Kb)  |  收藏  |  浏览/下载：232/1  |  提交时间：2010/12/24
Pacifastin  Serine Protease Inhibitors (Spis)  Pacifastin Light Chain Domain (Pld)  Eriocheir Sinensis  Mrna Expression  
Breaking seasonal limitation: year-round sporogenesis in the brown alga Laminaria saccharina by blocking the transport of putative sporulation inhibitors 期刊论文
AQUACULTURE, 2004, 卷号: 240, 期号: 1-4, 页码: 531-541
作者:  Pang, SJ;  Luning, K
Adobe PDF(233Kb)  |  收藏  |  浏览/下载：220/2  |  提交时间：2010/12/22
Laminaria Saccharina  Sporogenesis  Short-day Effect  Sporulation Inhibitors  Seaweed Cultivation  
Isolation, characterization and electron microscopic single particle analysis of the NADH : ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus 期刊论文
BIOCHEMISTRY, 2003, 卷号: 42, 期号: 10, 页码: 3032-3039
作者:  Peng, GH;  Fritzsch, G;  Zickermann, V;  Schaagger, H;  Mentele, R;  Lottspeich, F;  Bostina, M;  Radermacher, M;  Huber, R;  Stetter, KO;  Michel, H;  Michel, H, Max Planck Inst Biophys, Frankfurt, Germany
Adobe PDF(361Kb)  |  收藏  |  浏览/下载：138/1  |  提交时间：2010/11/18
Escherichia-coli  Mitochondrial Nadh  Bacterial  Protein  Purification  Translocation  Dehydrogenase  Flexibility  Inhibitors  Stability