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Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 7, 页码: 4452-4469
作者:  Luo, Jiao;  Wu, Ning;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian;  Wang, Baocheng;  Wang, Changhui;  Shi, Dayong
Adobe PDF(1638Kb)  |  收藏  |  浏览/下载:256/2  |  提交时间:2015/12/07
Anti-Angiogenic Properties of BDDPM, a Bromophenol from Marine Red Alga Rhodomela confervoides, with Multi Receptor Tyrosine Kinase Inhibition Effects 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 卷号: 16, 期号: 6, 页码: 13548-13560
作者:  Wang, Shuaiyu;  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Li, Xiangqian;  Liu, Shaofang;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2050Kb)  |  收藏  |  浏览/下载:238/1  |  提交时间:2015/12/07
Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 806-823
作者:  Wang, Li-Jun;  Wang, Shuai-Yu;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Wang, Bao-Cheng;  Luo, Jiao;  Yang, Meng;  Jin, Shui-Hua;  Shi, Da-Yong
Adobe PDF(1301Kb)  |  收藏  |  浏览/下载:244/0  |  提交时间:2015/06/15
Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl)-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating beta 1-Integrin/FAK Signaling 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 1010-1025
作者:  Wu, Ning;  Luo, Jiao;  Jiang, Bo;  Wang, Lijun;  Wang, Shuaiyu;  Wang, Changhui;  Fu, Changqing;  Li, Jian;  Shi, Dayong
Adobe PDF(995Kb)  |  收藏  |  浏览/下载:228/1  |  提交时间:2015/06/15
Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 60, 页码: 48822-48834
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(1045Kb)  |  收藏  |  浏览/下载:224/1  |  提交时间:2015/07/27
Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 2, 页码: 104-122
作者:  Wang, Li-Jun;  Jiang, Bo;  Wu, Ning;  Wang, Shuai-Yu;  Shi, Da-Yong
Adobe PDF(461Kb)  |  收藏  |  浏览/下载:263/0  |  提交时间:2015/06/15
Chemical Modification  Diabetes Mellitus  Natural Products  Patents  Ptp1b Inhibitors  Synthesized Compounds  Type 2 Diabetes Mellitus (2-dm)  
Xanthohumol, a Prenylated Chalcone from Beer Hops, Acts as an alpha-Glucosidase Inhibitor in Vitro 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 24, 页码: 5548-5554
作者:  Liu, Ming;  Yin, Hua;  Liu, Ge;  Dong, Jianjun;  Qian, Zhonghua;  Miao, Jinlai;  Miao, JL (reprint author), State Key Lab Biol Fermentat Engn Beer, Qingdao 266061, Peoples R China.
Adobe PDF(772Kb)  |  收藏  |  浏览/下载:276/0  |  提交时间:2015/06/11
HumuL.s LupuL.s L.  Xanthohumol  Alpha-glucosidase Inhibitor  
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao;  Shi, DY
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载:318/1  |  提交时间:2014/07/17
Type 2 Diabetes Mellitus  Protein Tyrosine Phosphatase 1b  Bromophenol  Anti-diabetic Activities  
Bromophenol coupled with diketopiperazine from marine red alga Symphyocladia latiuscula 期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2012, 卷号: 48, 期号: 4, 页码: 622-624
作者:  Xu, Xiuli;  Yin, Liyuan;  Fang, Nianqiao;  Fan, Xiao;  Song, Fuhang;  Xu, XL (reprint author), China Univ Geosci, Sch Ocean Sci, Beijing 100083, Peoples R China.
Adobe PDF(65Kb)  |  收藏  |  浏览/下载:259/0  |  提交时间:2013/09/24
Symphyocladia Latiuscula  Bromophenol  Diketopiperazine  
Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors 期刊论文
ARCHIV DER PHARMAZIE, 2012, 卷号: 345, 期号: 6, 页码: 444-453
作者:  Jiang, Bo;  Shi, Dayong;  Cui, Yongchao;  Guo, Shuju;  Shi, DY (reprint author), Chinese Acad Sci, R&D Ctr Marine Biotechnol, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(473Kb)  |  收藏  |  浏览/下载:260/1  |  提交时间:2013/09/24
Bromophenol  Protein Tyrosine Phosphatase 1b Inhibitor  Structure-activity Relationship  Type 2 Diabetes Mellitus