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Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:347/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:  Luo, Jiao;  Hou, Yufei;  Xie, Mengyue;  Ma, Wanli;  Shi, Dayong;  Jiang, Bo
Adobe PDF(2455Kb)  |  收藏  |  浏览/下载:308/0  |  提交时间:2020/09/25
CYC31  PTP1B inhibitor  insulin resistance  fatty acid oxidization  
Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 2, 页码: 806-823
作者:  Wang, Li-Jun;  Wang, Shuai-Yu;  Jiang, Bo;  Wu, Ning;  Li, Xiang-Qian;  Wang, Bao-Cheng;  Luo, Jiao;  Yang, Meng;  Jin, Shui-Hua;  Shi, Da-Yong
Adobe PDF(1301Kb)  |  收藏  |  浏览/下载:258/0  |  提交时间:2015/06/15
Structure, absolute configuration, and conformational study of resorcylic acid derivatives and related congeners from the fungus Penicillium brocae 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 50, 页码: 39870-39877
作者:  Zhang, Peng;  Meng, Ling-Hong;  Mandi, Attila;  Li, Xiao-Ming;  Kurtan, Tibor;  Wang, Bin-Gui
Adobe PDF(535Kb)  |  收藏  |  浏览/下载:329/0  |  提交时间:2015/07/27
structure, absolute configuration, and conformational study of resorcylic acid derivatives and related congeners from the fungus Penicillium brocae (vol 5, pg 39870, 2015) 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 62, 页码: 49904-49904
作者:  Zhang, Peng;  Meng, Ling-Hong;  Mandi, Attila;  Li, Xiao-Ming;  Kurtan, Tibor;  Wang, Bin-Gui
Adobe PDF(535Kb)  |  收藏  |  浏览/下载:230/0  |  提交时间:2015/07/27
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:  Shi, Dayong;  Guo, Shuju;  Jiang, Bo;  Guo, Chao;  Wang, Tao;  Zhang, Luyong;  Li, Jingya;  Shi, DY
Adobe PDF(662Kb)  |  收藏  |  浏览/下载:292/0  |  提交时间:2014/07/17
Bromophenol  Protein Tyrosine Phosphatase 1b Inhibitor  Db/db Mouse Model  Anti-diabetes Properties  
Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors 期刊论文
ARCHIV DER PHARMAZIE, 2012, 卷号: 345, 期号: 6, 页码: 444-453
作者:  Jiang, Bo;  Shi, Dayong;  Cui, Yongchao;  Guo, Shuju;  Shi, DY (reprint author), Chinese Acad Sci, R&D Ctr Marine Biotechnol, Inst Oceanol, Qingdao, Peoples R China.
Adobe PDF(473Kb)  |  收藏  |  浏览/下载:284/1  |  提交时间:2013/09/24
Bromophenol  Protein Tyrosine Phosphatase 1b Inhibitor  Structure-activity Relationship  Type 2 Diabetes Mellitus  
Synthesis and protein tyrosine phosphatase 1B inhibition activities of two new synthetic bromophenols and their methoxy derivatives 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 6, 页码: 1237-1242
作者:  Cui Yongchao;  Shi Dayong;  Hu Zhiqiang
Adobe PDF(413Kb)  |  收藏  |  浏览/下载:261/1  |  提交时间:2012/07/03
Protein Tyrosine Phosphatase 1b Inhibition  Bromophenol Derivatives  Synthesis  
Bromophenols in Marine Algae and Their Bioactivities 期刊论文
MARINE DRUGS, 2011, 卷号: 9, 期号: 7, 页码: 1273-1292
作者:  Liu, Ming;  Hansen, Poul Erik;  Lin, Xiukun
Adobe PDF(251Kb)  |  收藏  |  浏览/下载:211/0  |  提交时间:2012/07/03
Bromophenols  Marine Algae  Bioactivity  
Synthesis of three bromophenols from red algae as PTP1B inhibitors 期刊论文
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 1, 页码: 68-74
作者:  Guo Shuju;  Li Jing;  Li Ting;  Shi Dayong;  Han Lijun
Adobe PDF(360Kb)  |  收藏  |  浏览/下载:414/0  |  提交时间:2012/07/03
Bromophenols  Synthesis  Ptp1b Inhibitory Activity