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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载：31/0  |  提交时间：2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Analysis of differentially expressed genes in the sea cucumber Apostichopus japonicus under heat stress 期刊论文
ACTA OCEANOLOGICA SINICA, 2023, 卷号: 42, 期号: 11, 页码: 117-126
作者:  Xu, Dongxue;  Zhang, Jingjing;  Song, Wenqi;  Sun, Lina;  Liu, Ji;  Gu, Yuanxue;  Chen, Yanru;  Xia, Bin
收藏  |  浏览/下载：8/0  |  提交时间：2024/06/04
Apostichopus japonicus  heat stress  RNA-seq  protein processing  extracellular matrix  
Autophagy contributes to increase the content of intracellular free amino acids in hard clam (Mercenaria mercenaria) during prolonged exposure to hypersaline environments 期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:  Zhou, Cong;  Yang, Mei-jie;  Hu, Zhi;  Zou, Yan;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Song, Hao;  Zhang, Tao
Adobe PDF(5375Kb)  |  收藏  |  浏览/下载：216/1  |  提交时间：2023/11/30
Hyposalinity  Hypersalinity  Transcriptome  Autophagy  Free amino acids  
Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 249, 页码: 10
作者:  Huo, Da;  Su, Fang;  Yang, Hongsheng;  Sun, Lina
收藏  |  浏览/下载：62/0  |  提交时间：2023/11/16
Thermal stress  Stress response  Defense mechanism  Extracellular vesicles  MicroRNA  Echinoderm  
Characterizing the Status of Energetic Metabolism of Dinoflagellate Resting Cysts under Mock Conditions of Marine Sediments via Physiological and Transcriptional Measurements 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 23, 页码: 16
作者:  Li, Fengting;  Yue, Caixia;  Deng, Yunyan;  Tang, Ying Zhong
Adobe PDF(4536Kb)  |  收藏  |  浏览/下载：176/0  |  提交时间：2023/02/01
ATP content  energetic metabolism  resting cyst  Scrippsiella acuminata  tricarboxylic acid cycle  viability  
Full-length transcriptome analysis of the bloom-forming dinoflagellate Akashiwo sanguinea by single-molecule real-time sequencing 期刊论文
FRONTIERS IN MICROBIOLOGY, 2022, 卷号: 13, 页码: 12
作者:  Chen, Tiantian;  Liu, Yun;  Song, Shuqun;  Bai, Jie;  Li, Caiwen
Adobe PDF(3443Kb)  |  收藏  |  浏览/下载：119/0  |  提交时间：2023/01/04
Akashiwo sanguinea  harmful algal blooms  full-length transcript  single molecule real-time sequencing  reference resource  
Metabolomic and transcriptomic analyses reveal response mechanisms of juvenile flounder (Paralichthys olivaceus) to sublethal methylmercury 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 15
作者:  Ren, Zhonghua;  Ning, Junhao;  Cao, Liang;  Liu, Jinhu;  Zhan, Junfei;  Wang, Zhikang;  Yu, Junbao;  Yang, Jisong;  Lv, Zhenbo
Adobe PDF(4236Kb)  |  收藏  |  浏览/下载：170/0  |  提交时间：2023/01/04
methylmercury  paralichthys olivaceus  growth  metabolomic  transcriptomic  response mechanism  
Effects of modified clay on the formation of Phaeocystis globosa colony revealed by physiological and transcriptomic analyses 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 838, 页码: 12
作者:  Ren, Xiangzheng;  Yu, Zhiming;  Song, Xiuxian;  Zhu, Jianan;  Wang, Wentao;  Cao, Xihua
Adobe PDF(2585Kb)  |  收藏  |  浏览/下载：278/0  |  提交时间：2022/07/18
Phaeocystis globosa  Modi fied clay  Colony formation  Oxidative stress  Photosynthetic behaviour  Transcriptome  
Warming northward shifting southern limits of the iconic temperate seagrass (Zostera marina) 期刊论文
ISCIENCE, 2022, 卷号: 25, 期号: 8, 页码: 18
作者:  Xu, Shaochun;  Zhang, Yu;  Zhou, Yi;  Xu, Shuai;  Yue, Shidong;  Liu, Mingjie;  Zhang, Xiaomei
收藏  |  浏览/下载：159/0  |  提交时间：2023/01/06
Optimizing cryopreservation of sea cucumber (Apostichopus japonicus) sperm using a programmable freezer and computer-assisted sperm analysis 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 17
作者:  Xu, Shuai;  Liu, Shilin;  Sun, Jingchun;  Zhang, Libin;  Lin, Chenggang;  Sun, Lina;  Xing, Lili;  Jiang, Chunxi;  Yang, Hongsheng
Adobe PDF(4199Kb)  |  收藏  |  浏览/下载：223/0  |  提交时间：2022/12/09
Apostichopus japonicus  sperm  cryopreservation  motility  CASA  programmable freezer