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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:  Sun, Hao;  Bai, Xiaoyi;  Zhang, Yiting;  Gao, Yanan;  Dai, Jiajia;  Xing, Pan;  Zhu, Jiqiang;  Liu, Ruihua;  Wang, Zemin;  Li, Xiangqian
收藏  |  浏览/下载:4/0  |  提交时间:2024/06/04
Anti-tumor  SHP2  Orthosteric inhibitor  Apoptosis  Bromophenol  
CRISPR/Cas12a controlled chemiluminescence resonance energy transfer sensor for detection of carcinoembryonic antigen 期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 卷号: 401, 页码: 7
作者:  Zhou, Yanmei;  Xie, Shupu;  Li, Mingjie;  Xin, Liantao;  Zhang, Xiaoru;  Liu, Yi
收藏  |  浏览/下载:24/0  |  提交时间:2024/04/07
CRET  Hemin/G-quadruplexes  CRISPR/Cas12a  CEA  
Lack of Hematodinium microscopic detection in crustaceans at the northern and southern ends of the Wadden Sea and an update of its distribution in Europe 期刊论文
MARINE BIOLOGY, 2024, 卷号: 171, 期号: 3, 页码: 8
作者:  Huang, Qian;  Waser, Andreas M.;  Li, Caiwen;  Thieltges, David W.
收藏  |  浏览/下载:25/0  |  提交时间:2024/04/07
Parasitic dinoflagellate  Host diversity  Distribution  
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载:28/0  |  提交时间:2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 266, 页码: 11
作者:  Ding, Kui;  Xu, Qinzeng;  Zhang, Xuelei;  Liu, Shilin
Adobe PDF(3947Kb)  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/04/07
Apostichopus japonicus  BDE-47  Nervous system  UPLC-Triple-TOF-MS  Metabolite  Neurotoxicity  
Autophagy contributes to increase the content of intracellular free amino acids in hard clam (Mercenaria mercenaria) during prolonged exposure to hypersaline environments 期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:  Zhou, Cong;  Yang, Mei-jie;  Hu, Zhi;  Zou, Yan;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Song, Hao;  Zhang, Tao
Adobe PDF(5375Kb)  |  收藏  |  浏览/下载:212/1  |  提交时间:2023/11/30
Hyposalinity  Hypersalinity  Transcriptome  Autophagy  Free amino acids  
ROS-induced moderate autophagy of haemocytes confers resistance of Mercenaria mercenaria to air exposure stress 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
作者:  Zhou, Cong;  Zou, Yan;  Hu, Zhi;  Yang, Mei-jie;  Shi, Pu;  Li, Yong-ren;  Guo, Yong-jun;  Zhang, Tao;  Song, Hao
Adobe PDF(8330Kb)  |  收藏  |  浏览/下载:41/1  |  提交时间:2024/04/07
Air exposure  Resistance  Haemocytes  Oxidative stress  Autophagy  
Chemiluminescence Sensor for miRNA-21 Detection Based on CRISPR-Cas12a and Cation Exchange Reaction 期刊论文
ANALYTICAL CHEMISTRY, 2023, 页码: 8
作者:  Zhou, Yanmei;  Xie, Shupu;  Liu, Bo;  Wang, Cong;  Huang, Yibo;  Zhang, Xiaoru;  Zhang, Shusheng
收藏  |  浏览/下载:76/0  |  提交时间:2023/12/13
Evidence that offshore wind farms might affect marine sediment quality and microbial communities 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 856, 页码: 10
作者:  Wang, Ting;  Ru, Xiaoshang;  Deng, Beini;  Zhang, Chenxi;  Wang, Xu;  Yang, Bo;  Zhang, Libin
Adobe PDF(2727Kb)  |  收藏  |  浏览/下载:129/0  |  提交时间:2023/01/04
Offshore wind farm  Sediment  Heavy metals  Environmental evaluation  Benthic microbial community structures  
Confocal Raman microscopy for assessing effects of preservation methods on symbiotic deep-sea mussel gills 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 12
作者:  He, Wanying;  Wang, Minxiao;  Li, Mengna;  Zhong, Zhaoshan;  Chen, Hao;  Xi, Shichuan;  Luan, Zhendong;  Li, Chaolun;  Zhang, Xin
Adobe PDF(4373Kb)  |  收藏  |  浏览/下载:202/0  |  提交时间:2023/02/01
confocal Raman microscopy  symbiotic deep-sea mussel  preservation methods  Raman imaging  Raman signals