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Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
Adobe PDF(824Kb)  |  收藏  |  浏览/下载：313/0  |  提交时间：2019/08/21
Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：317/0  |  提交时间：2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
A Putative Insulin-like Androgenic Gland Hormone Receptor Gene Specifically Expressed in Male Chinese Shrimp 期刊论文
ENDOCRINOLOGY, 2018, 卷号: 159, 期号: 5, 页码: 2173-2185
作者:  Guo, Qing;  Li, Shihao;  Lv, Xinjia;  Xiang, Jianhai;  Sagi, Amir;  Manor, Rivka;  Li, Fuhua
Adobe PDF(2747Kb)  |  收藏  |  浏览/下载：389/0  |  提交时间：2019/08/21
Differential gene expression in the body wall of the sea cucumber (Apostichopus japonicus) under strong lighting and dark conditions 期刊论文
ACTA OCEANOLOGICA SINICA, 2018, 卷号: 37, 期号: 5, 页码: 54-66
作者:  Zhang Libin;  Feng Qiming;  Sun Lina;  Fang Yan;  Xu Dongxue;  Zhang Tao;  Yang Hongsheng
Adobe PDF(337Kb)  |  收藏  |  浏览/下载：233/0  |  提交时间：2019/07/15
sea cucumber  Apostichopus japonicus  gene expression  dark  light  body wall  
CPAP3 proteins in the mineralized cuticle of a decapod crustacean 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 12
作者:  Abehsera, Shai;  Zaccai, Shir;  Mittelman, Binyamin;  Glazer, Lilah;  Weil, Simy;  Khalaila, Isam;  Davidov, Geula;  Bitton, Ronit;  Zarivach, Raz;  Li, Shihao;  Li, Fuhua;  Xiang, Jianhai;  Manor, Rivka;  Aflalo, Eliahu D.;  Sagi, Amir
Adobe PDF(2541Kb)  |  收藏  |  浏览/下载：347/0  |  提交时间：2019/08/21
Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 13
作者:  Yue, Xin;  Huan, Pin;  Hu, Yonghua;  Liu, Baozhong
Adobe PDF(1951Kb)  |  收藏  |  浏览/下载：291/0  |  提交时间：2019/08/21
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载：236/0  |  提交时间：2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes  
The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade 期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 1, 页码: 55-69
作者:  Xu, Qi;  Wang, Lijun;  Luo, Jiao;  Shi, Dayong
Adobe PDF(2267Kb)  |  收藏  |  浏览/下载：219/0  |  提交时间：2018/04/02
Type 2 Diabetes Mellitus  Insulin Resistance  Insulin Secretion  Targets  Mechanism  Drugs  
The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 7, 页码: 861-878
作者:  Jin, Qiu;  Yu, Huahua;  Li, Pengcheng
Adobe PDF(757Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2019/08/21
Anti-obesity  marine-derived  digestive enzyme  appetite  fat absorption  adipogenesis  thermogenesis  utilization