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Global profiling and characterization of Japanese flounder (Paralichthys olivaceus) kidney microRNAs regulated by Edwardsiella tarda infection in a time-dependent fashion 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 93, 页码: 766-780
作者:  Li, Wen-rui;  Hu, Yong-hua;  Jiang, Shuai;  Sun, Li
Adobe PDF(4935Kb)  |  收藏  |  浏览/下载：320/0  |  提交时间：2020/01/03
microRNA  Paralichthys olivaceus  Edwardsiella tarda  Infection  
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
Adobe PDF(824Kb)  |  收藏  |  浏览/下载：298/0  |  提交时间：2019/08/21
Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：297/0  |  提交时间：2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
A comparative study on oxidative stress response in the hepatopancreas and midgut of the white shrimp Litopenaeus vannamei under gradual changes to low or high pH environment 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 76, 页码: 27-34
作者:  Han, Si-yin;  Wang, Meng-qiang;  Wang, Bao-jie;  Liu, Mei;  Jiang, Ke-yong;  Wang, Lei
Adobe PDF(2362Kb)  |  收藏  |  浏览/下载：313/0  |  提交时间：2019/08/21
Litopenaeus vannamei  Hepatopancreas  Midgut  Gradual-low pH  Gradual-high pH  Antioxidant  
Adaptation of the white shrimp Litopenaeus vannamei to gradual changes to a low-pH environment 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 149, 页码: 203-210
作者:  Han, Si-yin;  Wang, Bao-jie;  Liu, Mei;  Wang, Meng-qiang;  Jiang, Ke-yong;  Liu, Xin-wei;  Wang, Lei
Adobe PDF(933Kb)  |  收藏  |  浏览/下载：282/0  |  提交时间：2019/08/21
Litopenaeus vannamei  Gradual-low pH  Mortality  Growth performance  Osmoregulation  Vibrio parahemolyticus  
Comparative sensitivity of the hepatopancreas and midgut in the white shrimp Litopenaeus vannamei to oxidative stress under cyclic serious/medium hypoxia 期刊论文
AQUACULTURE, 2018, 卷号: 490, 页码: 44-52
作者:  Han, Si-yin;  Wang, Meng-qiang;  Liu, Mei;  Wang, Bao-jie;  Jiang, Ke-yong;  Wang, Lei
Adobe PDF(621Kb)  |  收藏  |  浏览/下载：247/0  |  提交时间：2019/08/21
Litopenaeus vannamei  Hepatopancreas  Midgut  Cyclic serious/medium hypoxia  Oxidative stress  Gene expression  
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Adobe PDF(5208Kb)  |  收藏  |  浏览/下载：335/0  |  提交时间：2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:  Wang, Li-Jun;  Guo, Chuan-Long;  Li, Xiang-Qian;  Wang, Shuai-Yu;  Jiang, Bo;  Zhao, Yue;  Luo, Jiao;  Xu, Kuo;  Liu, Hua;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
收藏  |  浏览/下载：309/0  |  提交时间：2019/07/15
bromophenol hybrids  anticancer  structure-activity relationships  ROS  apoptotic pathway  
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359
作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo;  Zhang, Ren-Shuai;  Shi, Da-Yong
Adobe PDF(1863Kb)  |  收藏  |  浏览/下载：317/0  |  提交时间：2017/10/09
Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity  
The oyster genome reveals stress adaptation and complexity of shell formation 期刊论文
NATURE, 2012, 卷号: 490, 期号: 7418, 页码: 49-54
作者:  Zhang, Guofan;  Fang, Xiaodong;  Guo, Ximing;  Li, Li;  Luo, Ruibang;  Xu, Fei;  Yang, Pengcheng;  Zhang, Linlin;  Wang, Xiaotong;  Qi, Haigang;  Xiong, Zhiqiang;  Que, Huayong;  Xie, Yinlong;  Holland, Peter W. H.;  Paps, Jordi;  Zhu, Yabing;  Wu, Fucun;  Chen, Yuanxin;  Wang, Jiafeng;  Peng, Chunfang;  Meng, Jie;  Yang, Lan;  Liu, Jun;  Wen, Bo;  Zhang, Na;  Huang, Zhiyong;  Zhu, Qihui;  Feng, Yue;  Mount, Andrew;  Hedgecock, Dennis;  Xu, Zhe;  Liu, Yunjie;  Domazet-Loso, Tomislav;  Du, Yishuai;  Sun, Xiaoqing;  Zhang, Shoudu;  Liu, Binghang;  Cheng, Peizhou;  Jiang, Xuanting;  Li, Juan;  Fan, Dingding;  Wang, Wei;  Fu, Wenjing;  Wang, Tong;  Wang, Bo;  Zhang, Jibiao;  Peng, Zhiyu;  Li, Yingxiang;  Li, Na;  Wang, Jinpeng;  Chen, Maoshan;  He, Yan;  Tan, Fengji;  Song, Xiaorui;  Zheng, Qiumei;  Huang, Ronglian;  Yang, Hailong;  Du, Xuedi;  Chen, Li;  Yang, Mei;  Gaffney, Patrick M.;  Wang, Shan;  Luo, Longhai;  She, Zhicai;  Ming, Yao;  Huang, Wen;  Zhang, Shu;  Huang, Baoyu;  Zhang, Yong;  Qu, Tao;  Ni, Peixiang;  Miao, Guoying;  Wang, Junyi;  Wang, Qiang;  Steinberg, Christian E. W.;  Wang, Haiyan;  Li, Ning;  Qian, Lumin;  Zhang, Guojie;  Li, Yingrui;  Yang, Huanming;  Liu, Xiao;  Wang, Jian;  Yin, Ye;  Wang, Jun;  Wang, J (reprint author), BGI Shenzhen, Shenzhen 518083, Peoples R China.
Adobe PDF(712Kb)  |  收藏  |  浏览/下载：1378/2  |  提交时间：2013/09/24
Transposable Elements  Crassostrea-gigas  Bivalve Mollusks  Parahox Genes  Proteins  Sequence  Evolution  Discovery  Apoptosis  Pathway