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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia;  Liu, Ming
收藏  |  浏览/下载：4/0  |  提交时间：2024/04/07
Acquired resistance  Cancer  NSCLC  JC-010a  SHP2  
Effects of modified clay on the formation of Phaeocystis globosa colony revealed by physiological and transcriptomic analyses 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 838, 页码: 12
作者:  Ren, Xiangzheng;  Yu, Zhiming;  Song, Xiuxian;  Zhu, Jianan;  Wang, Wentao;  Cao, Xihua
Adobe PDF(2585Kb)  |  收藏  |  浏览/下载：212/0  |  提交时间：2022/07/18
Phaeocystis globosa  Modi fied clay  Colony formation  Oxidative stress  Photosynthetic behaviour  Transcriptome  
Optimizing cryopreservation of sea cucumber (Apostichopus japonicus) sperm using a programmable freezer and computer-assisted sperm analysis 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 17
作者:  Xu, Shuai;  Liu, Shilin;  Sun, Jingchun;  Zhang, Libin;  Lin, Chenggang;  Sun, Lina;  Xing, Lili;  Jiang, Chunxi;  Yang, Hongsheng
Adobe PDF(4199Kb)  |  收藏  |  浏览/下载：176/0  |  提交时间：2022/12/09
Apostichopus japonicus  sperm  cryopreservation  motility  CASA  programmable freezer  
Massive Heat Shock Protein 70 Genes Expansion and Transcriptional Signatures Uncover Hard Clam Adaptations to Heat and Hypoxia 期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 14
作者:  Hu, Zhi;  Song, Hao;  Feng, Jie;  Zhou, Cong;  Yang, Mei-Jie;  Shi, Pu;  Yu, Zheng-Lin;  Li, Yong-Ren;  Guo, Yong-Jun;  Li, Hai-Zhou;  Zhang, Tao
Adobe PDF(7352Kb)  |  收藏  |  浏览/下载：167/0  |  提交时间：2022/07/18
Mercenaria mercenaria  HSP70  heat  hypoxia  adaptation  
Mechanisms of heat and hypoxia defense in hard clam: Insights from transcriptome analysis 期刊论文
AQUACULTURE, 2022, 卷号: 549, 页码: 11
作者:  Hu, Zhi;  Feng, Jie;  Song, Hao;  Zhou, Cong;  Yu, Zheng-Lin;  Yang, Mei-Jie;  Shi, Pu;  Guo, Yong-Jun;  Li, Yong-Ren;  Zhang, Tao
Adobe PDF(1663Kb)  |  收藏  |  浏览/下载：213/0  |  提交时间：2022/07/15
Mercenaria mercenaria  RNA-seq  Heat  Hypoxia  Global change  
Expression Patterns of the Heat Shock Protein 90 (Hsp90) Gene Suggest Its Possible Involvement in Maintaining the Dormancy of Dinoflagellate Resting Cysts 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 20, 页码: 18
作者:  Deng, Yunyan;  Li, Fengting;  Hu, Zhangxi;  Yue, Caixia;  Tang, Ying Zhong
Adobe PDF(9433Kb)  |  收藏  |  浏览/下载：186/0  |  提交时间：2022/01/05
dinoflagellate  dormancy  environmental cDNA library  heat shock protein 90 (Hsp90)  resting cysts  Scrippsiella trochoidea  temperature stress  
The Implication Inferred from the Expression of Small Heat-Shock Protein Genes in Dinoflagellate Resting Cysts Buried in Marine Sediment 期刊论文
DIVERSITY-BASEL, 2021, 卷号: 13, 期号: 10, 页码: 13
作者:  Deng, Yunyan;  Li, Fengting;  Hu, Zhangxi;  Yue, Caixia;  Tang, Ying Zhong
Adobe PDF(2302Kb)  |  收藏  |  浏览/下载：149/0  |  提交时间：2022/01/05
dinoflagellate  dormancy  environmental cDNA library  harmful algal blooms  marine sediment  resting cysts  resting stage persistence  small heat shock protein (sHsp)  
RNA-Seq analysis and WGCNA reveal dynamic molecular responses to air exposure in the hard clam Mercenaria mercenaria 期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 4, 页码: 2847-2859
作者:  Zhou, Cong;  Song, Hao;  Feng, Jie;  Hu, Zhi;  Yu, Zheng-Lin;  Yang, Mei-Jie;  Shi, Pu;  Li, Yong-Ren;  Guo, Yong-Jun;  Zhang, Tao
Adobe PDF(10947Kb)  |  收藏  |  浏览/下载：188/0  |  提交时间：2021/12/07
Air exposure  Mercenaria mercenaria  Response  Transcriptome  
Transcriptional Responses of the Heat Shock Protein 20 (Hsp20) and 40 (Hsp40) Genes to Temperature Stress and Alteration of Life Cycle Stages in the Harmful Alga Scrippsiella trochoidea (Dinophyceae) 期刊论文
BIOLOGY-BASEL, 2020, 卷号: 9, 期号: 11, 页码: 17
作者:  Deng, Yunyan;  Hu, Zhangxi;  Shang, Lixia;  Chai, Zhaoyang;  Tang, Ying Zhong
Adobe PDF(1504Kb)  |  收藏  |  浏览/下载：179/0  |  提交时间：2021/04/12
Scrippsiella trochoidea  resting cyst  dinoflagellate  harmful algal blooms  heat shock protein 20 (Hsp20)  heat shock protein 40 (Hsp40)  temperature stress  
Time course analysis of immunity-related gene expression in the sea cucumber Apostichopus japonicus during exposure to thermal and hypoxic stress 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 95, 页码: 383-390
作者:  Huo, Da;  Sun, Lina;  Zhang, Libin;  Yang, Hongsheng;  Liu, Shilin;  Sun, Jingchun;  Su, Fang
Adobe PDF(4097Kb)  |  收藏  |  浏览/下载：368/0  |  提交时间：2020/03/20
Anoxia  Heat stress  Global climate change  Holothurian  Echinoderm  Immune system  High temperature  Immune-associated genes  Stress response  Aquaculture