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Raptor/mTORC1 Acts as a Modulatory Center to Regulate Anti-bacterial Immune Response in Rockfish 期刊论文
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: 10, 页码: 14
作者:  Li, Kang;  Wei, Xiumei;  Zhang, Libin;  Chi, Heng;  Yang, Jialong
Adobe PDF(3990Kb)  |  收藏  |  浏览/下载:413/0  |  提交时间:2020/03/20
teleost  mTORC1  raptor  lymphocyte  immune regulation  evolution  
Dietary Recombinant Phycoerythrin Modulates the Gut Microbiota of H22 Tumor-Bearing Mice 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 12, 页码: 17
作者:  Qi, Hongtao;  Liu, Ying;  Qi, Xin;  Liang, Hui;  Chen, Huaxin;  Jiang, Peng;  Wang, Dongfeng
Adobe PDF(3429Kb)  |  收藏  |  浏览/下载:363/0  |  提交时间:2020/03/20
recombinant phycoerythrin  anti-tumor and immunomodulatory effects  intestinal flora  high-throughput sequencing  microbial barrier  
Structure-Dependent Modulation of Substrate Binding and Biodegradation Activity of Pirin Proteins toward Plant Flavonols 期刊论文
ACS CHEMICAL BIOLOGY, 2019, 卷号: 14, 期号: 12, 页码: 2629-2640
作者:  Guo, Bin;  Zhang, Yichen;  Hicks, Gregory;  Huang, Xingrong;  Li, Rongfeng;  Roy, Natalie;  Jia, Zongchao
Adobe PDF(6597Kb)  |  收藏  |  浏览/下载:274/0  |  提交时间:2020/03/20
Time course analysis of immunity-related gene expression in the sea cucumber Apostichopus japonicus during exposure to thermal and hypoxic stress 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 95, 页码: 383-390
作者:  Huo, Da;  Sun, Lina;  Zhang, Libin;  Yang, Hongsheng;  Liu, Shilin;  Sun, Jingchun;  Su, Fang
Adobe PDF(4097Kb)  |  收藏  |  浏览/下载:368/0  |  提交时间:2020/03/20
Anoxia  Heat stress  Global climate change  Holothurian  Echinoderm  Immune system  High temperature  Immune-associated genes  Stress response  Aquaculture  
Biogeochemical characteristics and ecological risk assessment of pharmaceutically active compounds (PhACs) in the surface seawaters of Jiaozhou Bay, North China 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 255, 页码: 12
作者:  Peng, Quancai;  Song, Jinming;  Li, Xuegang;  Yuan, Huamao;  Li, Ning;  Duan, Liqin;  Zhang, Qian;  Liang, Xianmeng
Adobe PDF(2964Kb)  |  收藏  |  浏览/下载:273/0  |  提交时间:2020/03/20
PhACs  Surface seawaters  Occurrence  Risk assessment  Jiaozhou Bay (JZB)  
Antibacterial metabolites from Ascidian-derived fungus Aspergillus clavatus AS-107 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 34, 页码: 30-34
作者:  Song, Qi;  Li, Xiao-Ming;  Hu, Xue-Yi;  Li, Xin;  Chi, Lu-Ping;  Li, Hong-Lei;  Wang, Bin-Gui
Adobe PDF(1341Kb)  |  收藏  |  浏览/下载:254/0  |  提交时间:2020/03/20
Ascidian-derived fungus  Aspergillus clavatus  Secondary metabolites  Antibacterial activity  
PI signal transduction and ubiquitination respond to dehydration stress in the red seaweed Gloiopeltis furcata under successive tidal cycles 期刊论文
BMC PLANT BIOLOGY, 2019, 卷号: 19, 期号: 1, 页码: 14
作者:  Liu, Shun;  Hu, Zi-Min;  Zhang, Quansheng;  Yang, Xiaoqi;  Critchley, Alan T.;  Duan, Delin
Adobe PDF(1484Kb)  |  收藏  |  浏览/下载:278/0  |  提交时间:2020/03/20
Seaweed  Dehydration  Ubiquitination  Phosphatidylinositol signaling system  Weighted gene co-expression network analysis  
H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:  Li, Fengli;  Wang, Jing;  Wu, Ning;  Zhang, Hua;  Li, Zheng;  Wei, Ning
Adobe PDF(1665Kb)  |  收藏  |  浏览/下载:208/0  |  提交时间:2020/03/20
5-FU  Drug resistance  STAT3  Hepatocellular carcinoma  MCL-1  PUMA  
β-葡聚糖在虹鳟生长、抗杀鲑气单胞菌及肠炎感染中的调节机制研究 学位论文
理学博士, 中国科学院海洋研究所: 中国科学院大学, 2019
作者:  纪利芹
Adobe PDF(10555Kb)  |  收藏  |  浏览/下载:252/0  |  提交时间:2019/12/31
Β-葡聚糖  虹鳟  杀鲑气单胞菌  免疫和代谢  肠炎  转录组  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载:307/0  |  提交时间:2020/03/20