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Two new alkaloids from Penicillium oxalicum EN-201, an endophytic fungus derived from the marine mangrove plant Rhizophora stylosa
Zhang, Peng1,2; Li, Xiao-Ming1; Liu, Hui1,2; Li, Xin1,2; Wang, Bin-Gui1
2015-09-01
发表期刊PHYTOCHEMISTRY LETTERS
卷号13期号:2015页码:160-164
文章类型Article
摘要Two new alkaloids including a new prenylated indole derivative possessing a piperidine moiety, penioxamide A (1), and a new decaturin analogue, 18-hydroxydecaturin B (2), were isolated and identified from Penicillium oxalicum EN-201, an endophytic fungus obtained from the inner tissue of the fresh leaves of marine mangrove plant Rhizophora stylosa. Their structures and absolute configurations were elucidated on the basis of the spectral data and CD analysis. Compound 1 bears the rare anti relative configuration in the bicyclo[2.2.2]diazaoctane ring, while compound 2 has a pyridinyl-a-pyrone substructure which is rare among natural products. Compounds 1 and 2 showed potent brine shrimp lethality with LD50 values of 5.6 and 2.3 mu M, respectively. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词Marine Mangrove Endophytic Fungus Penicillium Oxalicum Alkaloid Brine Shrimp Lethality
DOI10.1016/j.phytol.2015.06.009
收录类别SCI
语种英语
WOS记录号WOS:000362174600029
引用统计
被引频次:30[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/50939
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位实验海洋生物学重点实验室
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Zhang, Peng,Li, Xiao-Ming,Liu, Hui,et al. Two new alkaloids from Penicillium oxalicum EN-201, an endophytic fungus derived from the marine mangrove plant Rhizophora stylosa[J]. PHYTOCHEMISTRY LETTERS,2015,13(2015):160-164.
APA Zhang, Peng,Li, Xiao-Ming,Liu, Hui,Li, Xin,&Wang, Bin-Gui.(2015).Two new alkaloids from Penicillium oxalicum EN-201, an endophytic fungus derived from the marine mangrove plant Rhizophora stylosa.PHYTOCHEMISTRY LETTERS,13(2015),160-164.
MLA Zhang, Peng,et al."Two new alkaloids from Penicillium oxalicum EN-201, an endophytic fungus derived from the marine mangrove plant Rhizophora stylosa".PHYTOCHEMISTRY LETTERS 13.2015(2015):160-164.
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