Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria | |
Liu, Yang1,2 ; Li, Xiao-Ming1; Meng, Ling-Hong1,2; Wang, Bin-Gui1
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| 2015-06-01 | |
| 发表期刊 | PHYTOCHEMISTRY LETTERS
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| 卷号 | 12页码:232-236 |
| 文章类型 | Article |
| 摘要 | Three new polyketides, namely, asperochrins A-C (1-3), along with 12 known related derivatives (4-15), were isolated from Aspergillus ochraceus MA-15, a fungus obtained from the rhizospheric soil of marine mangrove plant Bruguiera gymnorrhiza. The structures of these compounds were elucidated on the basis of spectroscopic analysis and the absolute configurations of the new compounds were determined by CD experiments and modified Mosher's method. The X-ray crystallographic experiment of compound 4 disclosed its racemic nature as (+/-)-botryoisocoumarin A for the first time. The brine shrimp lethality and antibacterial activity of compounds 1-15 were evaluated. Compounds 1, 5, 6, 9, 11, and 15 showed inhibitory activity against aquatic pathogenic bacterial Aeromonas hydrophila, Vibrio anguillarum, and Vibrio harveyi. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| 关键词 | Mangrove Rhizospheric Fungus Aspergillus Ochraceus Secondary Metabolites Polyketide Derivatives Antibacterial Activity |
| DOI | 10.1016/j.phytol.2015.04.009 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356336400045 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/33079 |
| 专题 | 实验海洋生物学重点实验室 海洋生态与环境科学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 第一作者单位 | 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,et al. Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria[J]. PHYTOCHEMISTRY LETTERS,2015,12:232-236. |
| APA | Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,&Wang, Bin-Gui.(2015).Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria.PHYTOCHEMISTRY LETTERS,12,232-236. |
| MLA | Liu, Yang,et al."Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria".PHYTOCHEMISTRY LETTERS 12(2015):232-236. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Polyketides from the（696KB） | 期刊论文 | 出版稿 | 限制开放 | ODC PDDL | 浏览 | |
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