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Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria
Liu, Yang1,2; Li, Xiao-Ming1; Meng, Ling-Hong1,2; Wang, Bin-Gui1
2015-06-01
发表期刊PHYTOCHEMISTRY LETTERS
卷号12页码:232-236
文章类型Article
摘要Three new polyketides, namely, asperochrins A-C (1-3), along with 12 known related derivatives (4-15), were isolated from Aspergillus ochraceus MA-15, a fungus obtained from the rhizospheric soil of marine mangrove plant Bruguiera gymnorrhiza. The structures of these compounds were elucidated on the basis of spectroscopic analysis and the absolute configurations of the new compounds were determined by CD experiments and modified Mosher's method. The X-ray crystallographic experiment of compound 4 disclosed its racemic nature as (+/-)-botryoisocoumarin A for the first time. The brine shrimp lethality and antibacterial activity of compounds 1-15 were evaluated. Compounds 1, 5, 6, 9, 11, and 15 showed inhibitory activity against aquatic pathogenic bacterial Aeromonas hydrophila, Vibrio anguillarum, and Vibrio harveyi. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词Mangrove Rhizospheric Fungus Aspergillus Ochraceus Secondary Metabolites Polyketide Derivatives Antibacterial Activity
DOI10.1016/j.phytol.2015.04.009
收录类别SCI
语种英语
WOS记录号WOS:000356336400045
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/33079
专题实验海洋生物学重点实验室
海洋生态与环境科学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,et al. Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria[J]. PHYTOCHEMISTRY LETTERS,2015,12:232-236.
APA Liu, Yang,Li, Xiao-Ming,Meng, Ling-Hong,&Wang, Bin-Gui.(2015).Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria.PHYTOCHEMISTRY LETTERS,12,232-236.
MLA Liu, Yang,et al."Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria".PHYTOCHEMISTRY LETTERS 12(2015):232-236.
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